中国结核病数字服药依从性技术应用指南

doi:10.19982/j.issn.1000-6621.20250042

摘要/Abstract

摘要：

及时发现活动性结核病患者及结核分枝杆菌潜伏感染者并开展针对性治疗是控制结核病流行的重要手段。数字依从性技术(digital adherence technology,DAT)利用数字工具辅助卫生服务提供者监测和促进结核病患者和预防性服药者规范服药,可提高服药依从性。本指南系统总结了我国结核病防控领域已经应用的视频督导、电子药盒、手机APP、手机短信等DAT特点和实践证据,提出了应用DAT辅助抗结核治疗和结核病预防性治疗管理的建议,以期为各地利用DAT完善和优化结核病服药管理策略提供循证依据。

关键词: 结核, 自我遵嘱服药, 疾病管理, 数字依从性技术, 总结性报告(主题)

Abstract:

Timely identification of active tuberculosis (TB) patients and individuals with latent tuberculosis infection (LTBI), followed by targeted treatment, constitutes a critical strategy for TB epidemic control. Digital adherence technology (DAT) utilizes digital tools to assist healthcare providers in monitoring and promoting medication compliance among TB patients and those undergoing preventive treatment, thereby enhancing therapeutic adherence. This guideline systematically summarized the characteristics and practical evidence of DAT currently implemented in China’s TB prevention and control efforts, including video-observed therapy, electronic medication monitors, mobile applications, and SMS reminders. It further proposes recommendations for the application of DAT in supporting anti-TB treatment and TB preventive therapy, aiming to offer evidence-based guidance for the optimization and refinement of TB medication management strategies using DAT across various regions.

Key words: Tuberculosis, Self administration, Disease management, Digital adherence technology, Consensus development conferences as topic

中图分类号:

中国防痨协会结核病控制专业分会, 中国防痨协会青年分会, 《中国防痨杂志》编辑委员会. 中国结核病数字服药依从性技术应用指南[J]. 中国防痨杂志, 2025, 47(4): 385-397. doi: 10.19982/j.issn.1000-6621.20250042

Tuberculosis Control Branch of Chinese Antituberculosis Association, The Youth Branch of Chinese Antituberculosis Association, Editorial Board of Chinese Journal of Antituberculosis. Evidence-based guidelines for application of digital adherence technology in tuberculosis medication management in China[J]. Chinese Journal of Antituberculosis, 2025, 47(4): 385-397. doi: 10.19982/j.issn.1000-6621.20250042

图/表 2

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分级	具体描述
证据质量
高(A)	非常有把握:确信真实的效果接近于估算的效果
中(B)	对观察值有中等把握:真实的效果可能接近于估算的效果,但也有很大差异的可能性
低(C)	对观察值的把握有限:真实的效果可能与估算的效果存在很大差异
极低(D)	对观察值几乎没把握:估算的效果很不确定,常常远离真相
推荐强度
强(1)	明确显示干预措施利大于弊或弊大于利
弱(2)	利弊不确定或无论质量高低的证据均显示利弊相当