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中国防痨杂志 ›› 2012, Vol. 34 ›› Issue (9): 567-571.

• 论著 • 上一篇    下一篇

肺结核可疑症状者的发生频度和地区分布研究

李峻 刘小秋 李雪 姜世闻 张慧 王黎霞   

  1. 102206 北京,中国疾病预防控制中心结核病预防控制中心政策规划部(李峻、刘小秋、李雪、姜世闻),主任办公室(张慧、王黎霞)
  • 收稿日期:2012-07-25 出版日期:2012-09-10 发布日期:2012-12-17
  • 通信作者: 王黎霞 E-mail:wanglx@chinatb.org

Frequency and geographical distribution of people with suspected pulmonary tuberculosis symptoms in China

LI Jun,LIU Xiao-qiu, LI Xue,JIANG Shi-wen,ZHANG Hui,WANG Li-xia   

  1. Division of Policy and Program, National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
  • Received:2012-07-25 Online:2012-09-10 Published:2012-12-17
  • Contact: WANG Li-xia E-mail:wanglx@chinatb.org

摘要: 目的  了解目前我国肺结核可疑症状者在人群中的发生频度和地区分布。 方法  采用全国结核病流行病学调查办公室独立设计的调查问卷(问卷内容包括调查期间是否出现肺结核可疑症状及症状持续的时间)调查全国(不包括台港澳地区)15岁及以上人群中咳嗽、咯痰≥2周和(或)咯血的肺结核可疑症状者情况,分析不同人群和地区的肺结核可疑症状者率。采用多阶段分层整群等比例随机抽样的方法,共抽取全国31个省、自治区、直辖市(不包括台港澳地区)176个流行病学调查点447 563人,排除外出超过6个月者125 342人及15岁以下者58 940人,应检263 281人,现场问卷调查实检252 940人,受检率为96.1%。  结果  15岁及以上人群中肺结核可疑症状者比率为2.1%(5399/252 940)。男性肺结核可疑症状者比率为2.8%(3324/116 939),高于女性的1.5%(2075/136 001) (χ2=521.9,P<0.001);不同年龄组[15~岁组198例(占3.7%)、25~岁组292例(占5.4%)、35~岁组671例(占12.4%)、45~岁组945例(占17.5%)、55~岁组1403例(占26.0%)、65~岁组1197例(占22.2%)、75~岁组693例(占12.8%)]的可疑症状发生频度差异有统计学意义(χ2=2356.6,P<0.001),65岁及以上人群出现可疑症状的比率是15~65岁人群的2.976~3.335倍 (OR=3.150,95%CI=2.976~3.335);本地户籍人口中肺结核可疑症状者比率为2.2%(5026/229 923),高于非本地户籍人口的1.6%(373/23 017)(χ2=30.8,P<0.001);乡村地区的肺结核可疑症状者比率为2.5%(3488/138 057),高于城镇的1.7%(1911/114 883) (χ2=214.4,P<0.001);西部、中部和东部地区的肺结核可疑症状者比率分别为3.6%(2522/69 896)、2.0%(1603/80 926)和1.2%(1274/102 118),差异有统计学意义(χ2=1066.9,P<0.001)。平原、丘陵、山区和其他地区(除平原、丘陵和山区地理环境之外的地区)的肺结核可疑症状者比率分别为1.6%(1805/110 371)、2.1%(1551/74 009)、3.0%(1950/65 646)和3.2%(93/2941),差异有统计学意义(χ2=350.8,P<0.001)。 结论  应有针对性地采取各项措施,提高我国肺结核可疑症状者的发现水平。

关键词: 结核,肺/流行病学, 流行病学研究

Abstract: Objective  To understand the frequency and geographical distribution of people with suspected pulmonary tuberculosis (PTB) symptoms in China.   Methods  According to the fifth National Tuberculosis Epidemiological Sampling Survey, questionnaire survey was adopted to screen the people with suspected PTB symptoms (cough, expectoration ≥2 weeks and/or hemoptysis) aged 15 and above nationwide (excluding Hong Kong, Macao and Taiwan regions), the rates of people with suspected PTB symptoms in different population and areas were analyzed.   Results  The rate of people with suspected PTB symptoms in population aged 15 and above was 2.1% (5399/252 940). The rate in male was 2.8% (3324/116 939), higher than 1.5% (2075/136 001) of female (χ2=521.9, P<0.001). There was a significant statistic difference among the rate of different age groups (χ2=2356.6,P<0.001). People aged 65 and above was 2.976-3.335 times (OR=3.150,95%CI=2.976-3.335) more likely to develop suspected PTB symptoms than people aged 15 to 65. The rate in residence was 2.2% (5026/229 923), higher than 1.6% (373/23 017) of migrants (χ2=30.8, P<0.001). The rate in rural area was 2.5% (3488/138 057), higher than 1.7% (1911/114 883) of urban area (χ2=214.4, P<0.001). The rate in western, central and eastern regions were 3.6% (2522/69 896), 2.0% (1603/80 926) and 1.2% (1274/102 118) respectively, with significant statistic differences (χ2=1066.9, P<0.001). Significant statistic differences were also found among the rates in plain, hill, mountain and other areas (χ2=350.8, P<0.001).   Conclusion  Various measures should be taken to increase the case detection efficiency of people with suspected PTB symptoms in China.

Key words: Tuberculosis,pulmonary/epidemiology, Epidemiologic studies