关键词: 结核,肺, 疾病特征, 流行病学研究, 发病率, 数据说明,统计

Abstract:

Objective To analyze the epidemiological characteristics of the patients with bacterium-positive pulmonary tuberculosis (PTB) who were notified in 14 prefectures of Xinjiang Uygur Autonomous Region (“Xinjiang”) from 2008 to 2017, and to understand the epidemic situation of tuberculosis in Xinjiang. Methods A total of 104 306 patients with bacterium-positive PTB registered in the Infectious Disease Reporting & Information Management System in Xinjiang from January 2008 to December 2017 were analyzed. A descriptive statistical analysis method was used and the following epidemiological characteristics of the patients with bacterium-positive PTB, who were notified in 14 prefectures within 10 years, were analyzed: the report incidence, gender, age, occupation, etc. Results From 2008 to 2017, the average report incidence was 46.71/100000. The annual report incidence ranged from 35.40/100000 to 60.85/100000 and it was significant different in different years ( {\chi }_{\mathrm{trend}}^2 =3675.41, P<0.01). The report incidence was significant different too in different age groups of the patients (χ ²=951.02, P<0.01). Among the patients with bacterially confirmed PTB notified in 2008-2017, 57 437 patients were males while 46 869 patients were females, and the ratio of male to female was 1.23∶1. The report incidence rate in the male patients was 50.26/100000 and that was 43.80/100000 in the female patients. There was significant difference between male and female (χ ²=629.18, P<0.01). Comparing the report incidence in different prefectures, it was 69.64/100000 (28232/40540543) in Kashgar, 68.80/100000 (14096/20488832) in Hotan, 58.37/100000 (3711/6357778) in Altay, 58.05/100000 (14200/24462693) in Aksu, 49.34/100000 (2693/5458469) in Kizilsu Kirghiz, 48.82/100000 (13058/26746349) in Yili and 47.41/100000 (5703/12029999) in Tacheng. The report incidence in the above mentioned seven prefectures were higher than the average level of Xinjiang (46.71/100000). The number of bacterium-positive PTB patients in the four prefectures of southern Xinjiang (Kashgar, Aksu, Hotan and Kizilsu Kirghiz) accounted for 56.78% (59221/104306) of the total patients in Xinjiang. The occupational distribution of the patients showed that most of the patients were peasants who accounted for 70.14% (73157/104306) of the total patients, and then followed by the occupations of housework and unemployed persons, who accounted for 9.61% (10024/104306) of the total patients. Conclusion The trend of the average annual report incidence rate of bacterially confirmed PTB patients in Xinjiang decreased from 2008 to 2017. More than half of the patients come from the four prefectures of southern Xinjiang. The incidence rate are higher in elderly, male and farmer populations.

Key words: Tuberculosis,pulmonary, Disease attributes, Epidemiological studies, Incidence, Data description,statistics