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中国防痨杂志 ›› 2020, Vol. 42 ›› Issue (4): 322-326.doi: 10.3969/j.issn.1000-6621.2020.04.005

• 论著 • 上一篇    下一篇

2008—2018年广州市报告新发肺结核流行特征分析

沈鸿程,杜雨华,吴桂锋,雷宇,李铁钢,刘健雄()   

  1. 510095 广州市胸科医院
  • 收稿日期:2020-02-14 出版日期:2020-04-10 发布日期:2020-04-07
  • 通信作者: 刘健雄 E-mail:Ljxer64@qq.com
  • 基金资助:
    “十三五”国家科技重大专项(2018ZX10715004-002-017);广州市高水平临床重点专科和培育专科建设项目(穗卫函[2019]1555号);广东省转化医学创新平台培育建设项目B类(粤卫函[2018]1254号);广州市卫生健康科技重大项目(2020A031003)

Epidemiological characteristics of newly reported pulmonary tuberculosis from 2008 to 2018 in Guangzhou

SHEN Hong-cheng,DU Yu-hua,WU Gui-feng,LEI Yu,LI Tie-gang,LIU Jian-xiong()   

  1. Guangzhou Chest Hospital, Guangzhou 510095, China
  • Received:2020-02-14 Online:2020-04-10 Published:2020-04-07
  • Contact: Jian-xiong LIU E-mail:Ljxer64@qq.com

摘要:

目的 了解2008—2018年广州市报告新发肺结核流行特征及趋势。方法 通过《中国疾病预防控制信息系统》搜集2008—2018年广州市报告新发肺结核患者的性别、年龄、职业、地区分布、病原学分类等资料,共计144473例。2008—2018年广州市各年度及各区常住人口信息来源于广州市统计年鉴。对2008—2018年广州市报告新发肺结核的流行病学特征进行描述性分析。结果 2008—2018年广州市报告新发肺结核患者共计144473例,年均报告发病率为100.14/10万,报告发病率由2008年的148.44/10万(16556/11153400)下降至2018年的67.58/10万(10072/14904400),差异有统计学意义( χ 趋势 2 =6849.75,P<0.05)。2008—2018年广州市报告新发肺结核患者中,男性年均报告发病率为135.65/10万(100003/73722700),年均递减率为7.56%;女性年均报告发病率为63.04/10万(44470/70547300),年均递减率为7.38%,男女性间年均报告发病率差异有统计学意义(χ 2=18999.59,P<0.05);各年龄组中25~岁组报告新发患者最多,占23.88%(34505/144473);患者职业以家政、家务及待业人群占比最高(23.82%,34416/144473)。涂阳肺结核患者报告发病率呈逐年下降趋势,从2008年的41.31/10万(4608/11153400)下降至2018年的23.14/10万(3449/14904400)。结论 广州市报告新发肺结核疫情呈逐年下降趋势,需加强男性,青壮年,家政、家务及待业人员的结核病防控工作。

关键词: 结核,肺, 发病率, 流行病学研究, 小地区分析

Abstract:

Objective To understand the trend and epidemiological characteristics of newly reported pulmonary tuberculosis (PTB) cases in Guangzhou from 2008 to 2018. Methods Totally, 144473 information of newly reported PTB cases were collected from “China Information System for Disease Control and Prevention” from 2008 to 2018 in Guangzhou, including gender, age, occupation, regional distribution and pathogen classification. The annual and district resident population data of Guangzhou from 2008 to 2018 was derived from Guangzhou statistical yearbook. Descriptive analysis was conducted on the epidemiological characteristics of newly reported PTB in Guangzhou from 2008 to 2018. Results A total of 144473 PTB cases were newly reported from 2008 to 2018 in Guangzhou with an average annual newly reported incidence rate of 100.14/100000. The newly reported incidence declined from 148.44/100000 (16556/11153400) in 2008 to 67.58/100000 (10072/14904400) in 2018, which showed significant statistical difference ( χ trend 2 =6849.75, P<0.05). Among the newly reported PTB cases in Guangzhou from 2008 to 2018, the male average annual newly reported incidence was 135.65/100000 (100003/73722700) with an annual decline rate of 7.56%, whereas the female average annual newly reported incidence was 63.04/100000 (44470/70547300) with an annual decline rate of 7.38%, which showed significant statistical difference (χ 2=18999.59, P<0.05). The 25- years old group reported the most cases in each age group, accounting for 23.88% (34505/144473). House worker and unemployed population were the most common occupations of all the newly reported cases, accounting for 23.82% (34416/144473) of the total cases. The newly reported incidence of smear positive PTB declined year by year, from 41.31/100000 (4608/11153400) in 2008 to 23.14/100000 (3449/14904400) in 2018. Conclusion Newly reported PTB cases in Guangzhou shows a decreasing trend year by year. It is necessary to strengthen the prevention and control of tuberculosis among male, young adults, house worker and unemployed population.

Key words: Tuberculosis,pulmonary, Incidence, Epidemiologic studies, Small-area analysis