关键词: 结核, 肺/药物疗法, HIV感染, 重叠感染, 安徽省

Abstract: Objective  To understand the impact of active interventions on improving TB cure rate and reducing the fatality rate among Mtb/HIV co-infected patients in HIV high epidemic areas in Anhui province.  Methods   Information of the anti-TB treatment outcome of 199 Mtb/HIV co-infected patients registered from October 1 2006 to June 30 2009 in 7 high HIV epidemic counties was collected and analyzed. Results  Among the 199 Mtb/HIV co-infected patients,135 cases received antiretroviral therapy,192 cases received anti-TB treatment and 181 cases accepted full course supervision. Within 1 year after the completion of anti-TB treatment, of co-infected patients 48 cases recovered from TB, 113 cases completed the treatment course, 4 cases were transferred out, 4 cases died of TB, 21 cases died of non-TB diseases,1 case failed and 1 case was lost. The treatment success rate of Mtb/HIV co-infected patients was 83.9%（161/192）,the total fatality rate was 13.0%（25/192）while the fatality rate of TB was 2.1%（4/192）.Conclusion  The active cooperation between TB institutes and AIDS institutes of different levels would improve the detection of Mtb/HIV co-infected patients and provide timely diagnosis and treatment of both diseases which could effectively increase the TB cure rate and reduce the fatality rate among Mtb/HIV co-infected patients.

Key words: Tuberculosis, pulmonary/drug therapy, HIV infections, Superinfection, Anhui province