关键词: 结核, HIV感染, 重叠感染, 治疗结果, 随州市

Abstract: Objective  To evaluate the effect of the Fifth Round of Global Fund Program on Mtb/HIV co-infection control in Suizhou city. Methods  Quarterly and annual reports, special survey data were collected between the fourth quarter of 2006 and the fourth quarter of 2010 from Suizhou CDC. Database was established for statistical analysis. Results  During the program implementation period, 4077 TB patients were registered(among which, 21 cases were detected from TB screening among HIV/AIDS patients), the remaining 4056 cases received HIV antibody test, the examination rate reached 100.00%（4056/4056）, and HIV positive detection rate was 0.15%(6/4056). Regarding TB screening among HIV/AIDS patients, among 1521 cases of HIV/AIDS patients being followed-up, 92.64% (1409/1521) received TB screening. The corresponding TB detection rate was 1.49% (21/1409), which was 9.93 times of HIV detection rate among TB patients. A total of 27 Mtb/HIV patients were registered, all of them were administered anti-TB medication, the cure and treatment completion rate were 81.48% (22/27), treatment failure rate was 3.70% (1/27) and the death rate was 11.11% (3/27). The detection rate of active tuberculosis among HIV/AIDS patients decreased significantly from 5.17%(12/232) to 0.67%(2/300) in past 5 years（χ²=13.267，P=0.000）.Conclusion  The work of Mtb/HIV co-infection control should be focused on detection of TB cases among people living with HIV/AIDS. TB detection among HIV/AIDS patients, HIV tests among TB patients and anti-TB medication for Mtb/HIV patients are important in control of Mtb/HIV epidemic, and should carry out on a long-term basis.

Key words: Tuberculosis, HIV infections, Superinfection, Treatment outcome, Suizhou city