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中国防痨杂志 ›› 2023, Vol. 45 ›› Issue (5): 442-445.doi: 10.19982/j.issn.1000-6621.20230083

• 专题笔谈 • 上一篇    下一篇

基层结核病预防性治疗门诊建设的探索与展望

王大宽1, 张彬2, 刘自森3, 段伟焘3(), 高磊4()   

  1. 1 河南省郑州市中牟县疾病预防控制中心结核病防治科, 郑州 451450
    2 河南省郑州市中牟县疾病预防控制中心项目办, 郑州 451450
    3 河南省郑州市中牟县疾病预防控制中心办公室, 郑州 451450
    4 中国医学科学院病原生物学研究所, 北京 100730
  • 收稿日期:2023-03-22 出版日期:2023-05-10 发布日期:2023-04-25
  • 通信作者: 段伟焘,高磊 E-mail:dwtmail@sina.com;gaolei@ipbcams.ac.cn
  • 基金资助:
    中国医学科学院医学与健康科技创新工程(2021-I2M-1-037)

Exploration and prospect of the construction of primary tuberculosis preventive treatment clinic

Wang Dakuan1, Zhang Bin2, Liu Zisen3, Duan Weitao3(), Gao Lei4()   

  1. 1 Tuberculosis Prevention and Control Department, Zhongmu County Center for Disease Control and Prevention, Henan Province, Zhengzhou 451450, China
    2 Project Office, Zhongmu County Center for Disease Control and Prevention, Henan Province, Zhengzhou 451450, China
    3 Executive Office, Zhongmu County Center for Disease Control and Prevention, Henan Province, Zhengzhou 451450, China
    4 Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
  • Received:2023-03-22 Online:2023-05-10 Published:2023-04-25
  • Contact: Duan Weitao,Gao Lei E-mail:dwtmail@sina.com;gaolei@ipbcams.ac.cn
  • Supported by:
    Medical and Health Science and Technology Innovation Project, Chinese Academy of Medical Sciences(2021-I2M-1-037)

摘要:

我国是结核病高负担国家之一,要实现终止结核病流行的全球战略目标,需要有效利用结核病预防性治疗这一手段。针对HIV感染者、病原学阳性肺结核患者的密切接触者、免疫功能低下的临床高危个体开展结核分枝杆菌潜伏感染的检测和结核病预防性治疗,是降低结核病发病风险的重要措施。为积极探索适应基层的结核分枝杆菌潜伏感染高危人群的管理和干预模式,促进结核病预防性治疗策略的落地和优化,不断将结核病预防性治疗工作向专业化、精细化、精准化和可持续方向发展和转变,河南省郑州市中牟县疾病预防控制中心于2023年2月成立了独立的结核病预防性治疗门诊,并将在试运营期间及时针对门诊运行成效开展综合评价。本文中,笔者将基于基层建立独立的结核病预防性治疗门诊这一探索性工作的开展,细致地分析与总结结核病预防性治疗门诊建设的工作基础、主要内容,以及面临的困难和挑战。

关键词: 分枝杆菌,结核, 感染, 预防和防护用药, 门诊医疗

Abstract:

As one of the countries with a high burden of tuberculosis (TB) in the world, China needs to strengthen TB preventive treatment as a tool of achieving the global goals of the End TB. Identifying individuals with latent infection of TB and providing preventive treatment for those at high risk of developing active disease, such as HIV infections, close contacts of microbiologically confirmed pulmonary TB patients, and clinical immunosuppressed patients, are important measures to decline the risk of developing TB. In order to actively explore the management and intervention mode for the high-risk populations with latent TB infection at the grass-roots level, promote the implementation and optimization of TB preventive treatment strategies, and constantly develop and transform the preventive treatment in the direction of specialization, refinement, precision and sustainability, the Disease Prevention and Control Center of Zhongmu County, Zhengzhou City, Henan Province established an independent TB preventive treatment clinic in February 2023. During the trial operation period, a comprehensive evaluation will be conducted on the effectiveness of outpatient operations in a timely manner. In this paper, the author will carefully analyze and summarize the work basis and main content of the construction of primary TB preventive treatment clinic based on the exploratory work conducted in Zhongmu County.

Key words: Mycobacterium tuberculosis, Infection, Preventive and protective medication, Outpatient medical treatment

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