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中国防痨杂志 ›› 2019, Vol. 41 ›› Issue (11): 1145-1148.doi: 10.3969/j.issn.1000-6621.2019.11.001

• 展望与回顾 •    下一篇

建国70年来结核病化学治疗的历史进程要览

范琳(),熊坤龙,肖和平()   

  1. 200433 同济大学附属上海市肺科医院结核病临床研究中心 上海市结核病(肺)重点实验室
  • 收稿日期:2019-09-28 出版日期:2019-11-10 发布日期:2019-12-05

Historic review of anti-tuberculosis chemotherapy during seventy years of the People’s Republic of China

FAN Lin(),XIONG Kun-long,XIAO He-ping()   

  1. Shanghai Pulmonary Hospital, Clinic and Research Center of Tuberculosis, Shanghai Key Lab of Tuberculosis, Tongji University School of Medicine, Shanghai 200433,China
  • Received:2019-09-28 Online:2019-11-10 Published:2019-12-05

摘要:

结核病是一种古老的传染病,人类与其进行了长期的、艰苦卓绝的斗争,对结核病化学治疗的历史进程值得回顾与总结。随着中华人民共和国的成立及建国70年来我国各个方面的发展,从20世纪50年代初期第一代抗结核化学治疗药物及化学治疗方案的问世,到如今的抗结核新药的研发、问世,以及具有全新机制的化疗药物及治疗方案(包括预防性治疗)的探索、改进、完善,建国70年来结核病化学治疗的进展无不印证着人类彻底控制结核病的历程。

关键词: 结核, 药物疗法, 结核,抗多种药物性, 泛耐药结核病, 临床方案, 周年纪念日和特殊事件, 评论

Abstract:

Tuberculosis (TB) is an ancient disease. The historical process of chemotherapy of tuberculosis is worth reviewing and summing up due to its occurrence and development accompanied with human long term and arduous struggle against TB. With the founding of the People’s Republic of China and the development of various aspects of our country in the past 70 years, and from the advent of the first generation of anti-tuberculosis chemotherapy drugs and chemotherapy regimen in the early 1950s, to the research and development of new anti-tuberculosis drugs, as well as the exploration, improvement and perfection of chemotherapy regimen including preventive treatment, the progress of chemotherapy for tuberculosis in the 70 years since the founding of the People’s Republic of China confirms the course of complete control of tuberculosis in human history.

Key words: Tuberculosis, Drug therapy, Tuberculosis, multidrug-resistant, Extensively drug-resistant tuberculosis, Clinical protocols, Anniversaries and special events, Comment