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中国防痨杂志 ›› 2005, Vol. 27 ›› Issue (2): 117-119.

• 论著 • 上一篇    下一篇

宁波市住院肺结核病人耐药情况分析

沈建恩1；杨薇娜2；   

  1. 1.宁波市保黎医院 宁波 315031；2.宁波市疾病控制中心 宁波 315000；
  • 出版日期:2005-02-10 发布日期:2005-11-03

The situation of resistance to anti-TB drugs among inpatients

Shen Jian’en 1,Yang Weina.   

  1. 1.The Baoli Hospital of Ningbo, Zhejiang 315031, China
  • Online:2005-02-10 Published:2005-11-03

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摘要： 目的　了解宁波市住院肺结核病人的耐药情况,以及城市、城镇、城市流动人口及农村居民结核病的差异。方法 统计分析1992年1月-2003年12月在宁波保黎住院治疗的痰结核菌培养阳性病人的居民身份,并对全部培养阳性菌株进行菌型鉴定及4种抗结核药物(INH、SM、RFP、EMB)的耐药性测试。结果 初始耐药率为21.4%,其中城市11.5%、城镇14.1%、城市流动人口、19.4%和农村286%。获得性耐药率77.8%,其中城市、56.9%、城镇75%、城市流动人口85.7%和农村89%。结论 宁波保黎医院住院病人结核病耐药水平从高到底依次为农村、城市流动人口、城镇、城市。应加强农村和流动人口的治疗管理。

关键词: 结核, 初始耐药, 获得性耐药

Abstract: Objective To investigate resistant situation to anti-TB drugs among inpatients with pulmonary TB in the Baoli Hospital of Ningbo and the difference of drug resistance among patients from cities,towns and rural area and patients floating to cities. Methods Analysis was conducted on drug resistant tests to INH,SM,RFP and EMB of patients with sputum culture positive pulmonary TB hospitalized in our hospital from January 1992 to December 2003. Results The total initial drug resistance rate was 21.4%,11.5%,14.1%19.4% and 28.6% respectively for patients from cities,towns,other parts floating to cites and rural area. The total acquired drug resistance rate was 77.8%,56.9%,75%,85.7% and 89% respectively for patients from cites,towns,other parts floating to cites and rural area. Conclusion Resistance to Anti-TB drugs was the highest among rural inpatients and then,the inpatients floating to cites,from towns and cites.

Key words: Tuberculosis, Initial Drug-Resistance, Acquired drug resistance.

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