中国防痨杂志 ›› 2021, Vol. 43 ›› Issue (8): 847-852.doi: 10.3969/j.issn.1000-6621.2021.08.018
范雨鑫, 刘玫肖, 陈晶晶, 徐鑫, 张宇, 岳鹏, 曹文静, 宝福凯(), 柳爱华()
收稿日期:
2021-05-08
出版日期:
2021-08-10
发布日期:
2021-07-30
通信作者:
宝福凯,柳爱华
E-mail:baofukai@kmmu.edu.cn;liuaihua@kmmu.edu.cn
基金资助:
FAN Yu-xin, LIU Mei-xiao, CHEN Jing-jing, XU Xin, ZHANG Yu, YUE Peng, CAO Wen-jing, BAO Fu-kai(), LIU Ai-hua()
Received:
2021-05-08
Online:
2021-08-10
Published:
2021-07-30
Contact:
BAO Fu-kai,LIU Ai-hua
E-mail:baofukai@kmmu.edu.cn;liuaihua@kmmu.edu.cn
摘要:
结核分枝杆菌具有富含脂质的细胞壁,这种结构有助于结核分枝杆菌维持自身毒力并长期潜伏于宿主体内。脂阿拉伯甘露聚糖是结核分枝杆菌细胞壁中的重要组分,其复杂和独特的结构对结核分枝杆菌的生长、生存和毒力至关重要。作者综述了脂阿拉伯甘露聚糖的结构、生物合成途径、在免疫反应中的作用及在结核病诊断中的应用价值,为其可能作为一种新的结核病诊断生物标志物提供新的视野与思路。
范雨鑫, 刘玫肖, 陈晶晶, 徐鑫, 张宇, 岳鹏, 曹文静, 宝福凯, 柳爱华. 结核分枝杆菌脂阿拉伯甘露聚糖的免疫调节作用和诊断价值[J]. 中国防痨杂志, 2021, 43(8): 847-852. doi: 10.3969/j.issn.1000-6621.2021.08.018
FAN Yu-xin, LIU Mei-xiao, CHEN Jing-jing, XU Xin, ZHANG Yu, YUE Peng, CAO Wen-jing, BAO Fu-kai, LIU Ai-hua. Immunomodulatory effect of Mycobacterium tuberculosis lipoarabinomannan and its value on tuberculosis diagnosis[J]. Chinese Journal of Antituberculosis, 2021, 43(8): 847-852. doi: 10.3969/j.issn.1000-6621.2021.08.018
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