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中国防痨杂志 ›› 2018, Vol. 40 ›› Issue (4): 416-419.doi: 10.3969/j.issn.1000-6621.2018.04.013

• 综述 • 上一篇    下一篇

儿童结核病的诊断新进展

夏露,张峣,卢水华()   

  1. 201508 上海中医药大学中医系[夏露(在读博士生)]; 上海市公共卫生临床中心结核科(夏露、卢水华); 北京结核病诊疗技术创新联盟办公室(张峣)
  • 收稿日期:2017-12-28 出版日期:2018-07-10 发布日期:2018-05-14
  • 通信作者: 卢水华 E-mail:tubercle@shaphc.org
  • 基金资助:
    上海市公共卫生临床中心(中药黄芪有效成分对于结核感染小鼠DC细胞的免疫增强作用研究)(KY-GW-2018-29)

New progress in the diagnosis of childhood tuberculosis

Lu XIA,Yao ZHANG,Shui-hua LU()   

  1. *Department of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine (Department of Tuberculosis, Shanghai Public Health Clinical Center), Shanghai 201508, China
  • Received:2017-12-28 Online:2018-07-10 Published:2018-05-14
  • Contact: Shui-hua LU E-mail:tubercle@shaphc.org

摘要:

儿童结核病流行广泛,发病率、死亡率居高不下,WHO报道2016年全世界儿童结核病发病例数达到100万,死亡人数达到14万。为了控制儿童结核病的流行,WHO从战略上提出了“儿童结核病零死亡”的蓝图。但是儿童结核病缺乏典型症状,病变部位标本获取困难,结核分枝杆菌检出率低,儿童结核病诊断十分困难,零死亡率目前依然是巨大挑战。探寻最佳诊断方法,提高儿童结核病的早期诊断率十分必要,作者就儿童结核病的最新诊断技术做一系统性综述。

关键词: 儿童, 结核, 诊断,鉴别, 诊断技术和方法, 综述

Abstract:

Childhood tuberculosis is widespread, the morbidity and mortality are both high. WHO reported that the number of childhood tuberculosis have reached to 1 million all over the world, and the number of deaths have reached 140 thousand in 2016. In order to control the prevalence of childhood tuberculosis, WHO put forward a blueprint of “towards zero death for childhood tuberculosis”. However, childhood tuberculosis is without typical symptoms, and it is difficult to obtain specimens.Furthermore, the bacterial rate of Mycobacterium tuberculosis is low and diagnose of childhood tuberculosis is still very difficult. Therefore, zero death is still a huge challenge. It is very necessary to detect the best diagnostic method and improve the early diagnosis rate of childhood tuberculosis. This review is just of the latest diagnostic technology and procedures of childhood tuberculosis.

Key words: Pediatrics, Tuberculosis, Diagnosis,differential, Diagnostic techniques and procedures, Review