关键词: 结核, 肺/并发症, 肺疾病, 真菌性, 疾病易感性

Abstract: Objective To study the susceptible factors in patients with pulmonary tuberculosis complicated by fungal infection. Methods The clinical data of 522 patients with pulmonary tuberculosis, in which 54 cases were complicated by fungal infection (observation group), while 468 cases were not complicated by fungal infection (control group), were collected and analyzed retrospectively from July 2008 to July 2009. Results The involved factors of pulmonary tuberculosis complicated by fungal infection were correlated with sex, age, body mass index, clinical types, with or without the long-term use of antibiotics and glucocorticoids, diabetes mellitus and sputum smear-negative by acid-fast stain. There were significant differences in these factors between the observation group and the control group (P＜0.05). Through the analysis with the non-conditional logistic regression, 4 risk factors for the pulmonary tuberculosis patients were screened out, they were elderly, the long-term use of antibiotics or glucocorticoids, diabetes mellitus. Conclusion s The patients with elderly, the long-term use of antibiotics or glucocorticoids, diabetes mellitus need to be raised vigilance and need to be taken appropriate preventive control measures.

Key words: tuberculosis, pulmonary/complications, lung diseases, fungal, disease susceptibility