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中国防痨杂志 ›› 2020, Vol. 42 ›› Issue (12): 1333-1338.doi: 10.3969/j.issn.1000-6621.2020.12.016

• 综述 • 上一篇    下一篇


唐亮, 鲍玉成, 张文龙()   

  1. 300350 天津市海河医院骨科 国家中医药管理局中医药防治传染病重点研究室
  • 收稿日期:2020-05-08 出版日期:2020-12-10 发布日期:2020-12-24
  • 通信作者: 张文龙
  • 基金资助:

Effects of anti-tubercular agents on intestinal flora and its influence on the organism

TANG Liang, BAO Yu-cheng, ZHANG Wen-long()   

  1. Department of Orthopedics, Tianjin Haihe Hospital, TCM Key Research Laboratory for Infections Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin 300350, China
  • Received:2020-05-08 Online:2020-12-10 Published:2020-12-24
  • Contact: ZHANG Wen-long



关键词: 结核, 抗结核药, 细菌, 肠杆菌科, 因果律, 综述文献(主题)


The structure and metabolites of intestinal flora interact with the human body, to maintain the steady state of intestinal barrier, promote the balance of nutrition metabolism and immunity, and take participate in the pathological and physiological processes of various systems, tissues and organs. It has significant effect on the process of TB infection, pathogenesis, treatment and prognosis. However, the study of the effect of anti-tubercular agents on intestinal flora is limited. The authors reviewed the effect of intestinal flora on steady state of intestinal barrier, summarized the research results of the effect of anti-tubercular agents on intestinal flora, expanded related clinical issues, and discussed the extensive effect of intestinal flora changes on the organism.

Key words: Tuberculosis, Antitubercular agents, Bacteria, Enterobacteriaceae, Causality, Review literature as topic