关键词: 超声检查,介入性, 胸壁, 结核, 脓肿, 投药,局部, 疗效比较研究

Abstract:

Objective To explore the value of real-time ultrasound-guided pumping and rinsing plus drug injection in the treatment of chest wall tuberculous abscess. Methods Retrospective analysis of 40 cases of patients with tuberculous abscess of chest wall diagnosed by GeneXpert MTB/RIF from December 2011 to December 2016 in Integrated Chinese and Western Medicine Hospital of Zhejiang Province. All patients were randomly divided into two groups based on standard H-R-Z-E oral anti-tuberculosis treatment. The control group consisted of 20 patients. Based on oral anti-tuberculosis drug treatment, ultrasound-guided abscess pumping and rinsing were performed on tuberculous abscess of chest wall until the rinse water was clear. The observation group consisted of 20 patients treated with oral anti-tuberculosis drugs. Ultrasound-guided purulent pumping and saline rinsing were performed in patients with chest wall tuberculous abscess. Anti-tuberculosis drugs and glucocorticoids (Isoniazid injection,2 ml∶100 mg;Dexamethasone injection,1 ml∶2 mg) were injected twice a week according to the volume of pus extracted. The total effective rate of treatment of pathological changes was compared between the two groups. Results The treatment time of the two groups was limited to 12 months. The total effective rate of observation group was 95.0% (19/20) higher than 45.0% (9/20) of control group,the difference was statistically significant (χ ²=9.643,P=0.002). Conclusion On the basis of standard H-R-Z-E oral anti-tuberculosis drugs, real-time ultrasound-guided anti-tuberculosis drug injection is a reliable minimally invasive interventional therapy for the treatment of tuberculous abscess of the chest wall.

Key words: Ultrasonography,interventional, Thoracic wall, Tuberculosis, Abscess, Administration,topical, Comparative effectiveness research