Email Alert | RSS    帮助

中国防痨杂志 ›› 2018, Vol. 40 ›› Issue (12): 1271-1274.doi: 10.3969/j.issn.1000-6621.2018.12.006

• 论著 • 上一篇    下一篇

负压封闭引流技术在淋巴结结核治疗中的应用

杨磊1,张金贵1(),金锋2()   

  1. 1. 251700 山东省滨州市中心医院胸外科
    2. 山东大学附属山东省胸科医院胸外科
  • 收稿日期:2018-10-16 出版日期:2018-12-10 发布日期:2018-12-10

Evaluation of vacuum sealing drainage in the treatment of cervical lymph node tuberculosis

YANG Lei1,ZHANG Jin-gui1(),JIN Feng2()   

  1. 1. Department of Thoracic Surgery, Binzhou Central Hospital, Binzhou 251700,China
  • Received:2018-10-16 Online:2018-12-10 Published:2018-12-10

摘要:

目的 探讨负压封闭引流 (vacuum sealing drainage,VSD) 技术在淋巴结结核治疗中的应用经验及疗效。方法 搜集山东省滨州市中心医院2013年1月至2017年1月采用VSD治疗54例淋巴结结核患者的临床资料,其中男23例,女31例。术前进行标准化抗结核药物治疗4~6周,采用颈部CT增强扫描精准评估脓腔位置、范围及周围淋巴结病变情况,然后手术彻底清除脓肿、窦道,同时进一步行区域淋巴结清扫,并行VSD治疗[负压值为-125~-450mm Hg(1mm Hg=0.133kPa),持续负压吸引1~2周,每7天更换1次敷料];再通过评估创面肉芽生长情况进行二期缝合或转移皮瓣修复缝合;上述治疗结束后继续规范口服抗结核药物6~9个月,并电话或门诊随访6~12个月。统计创面愈合时间、复发情况,并进行分析、总结。结果 全组患者无围手术期死亡和并发症,54例患者均为一次性治愈,创面愈合时间为7~15d,住院治疗时间最短者7d,最长者22d,平均住院时间(11.23±7.62)d。患者均在化疗疗程结束后停药,随访6~12个月无复发。结论 应用术前精准评估+术中彻底病灶清除并区域淋巴结清扫+VSD治疗+二期缝合术治疗淋巴结结核,对于创面愈合、避免或减少复发、缩短住院时间有明显效果。

关键词: 结核, 淋巴结, 引流术, 负压伤口疗法, 治疗结果

Abstract:

Objective To evaluate the application of vacuum sealing drainage (VSD) in cervical lymph node tuberculosis (TB).Methods Between Jan 2013 and Jan 2017, a total of 54 patients (23 males and 31 females) who were admitted to Binzhou Central Hospital and diagnosed as cervical lymph node TB were included in the retrospective study. All enrolled patients had received standard anti-TB therapy (4-6 weeks), and then cervical lymph nodes were evaluated via CT. Surgical procedures, such as abscess drainage, lymph node resection, and second suture or flap tamponade suture, were performed. Meanwhile, all were treated with VSD therapy (-125--450mm Hg,1mm Hg=0.133 kPa) about 1-2 weeks. Finally, all patients were followed up 6-12months after 6-9months of anti-TB therapy, wound healing time and the recurrence rate were obtained for statistical analysis.Results There were no perioperative death, no serious complications and no recurrence within a follow-up period. All 54 patients were cured, the wound healing time ranged from 7 to 15days, the hospitalization time ranged from 7 to 22days, and the mean treatment time was (11.23±7.62)days.Conclusion The application of the combination of pre-surgical evaluation, abscess drainage+lymph node resection, VSD treatment and second suture was helpful to repair wound, reduce recurrence rate and hospitalization time.

Key words: Tuberculosis, lymph node, Drainage, Negative-pressure wound therapy, Treatment outcome