糖尿病对耐多药肺结核的影响与对策

doi:10.3969/j.issn.1000-6621.2018.09.018

摘要/Abstract

摘要：

随着糖尿病患病率的增加和耐多药肺结核(MDR-PTB)的流行,糖尿病对MDR-PTB的影响越来越受到关注。笔者汇总国内外文献资料对MDR-PTB并发糖尿病的发病情况、临床特征、影像学特点、呼吸道其他细菌感染情况、抗结核药物的选择和应用,以及治疗转归进行分析,探究糖尿病对MDR-PTB的影响。结果提示,糖尿病是MDR-PTB的重要危险因素,尽早有效控制血糖、合理选择有效的抗结核药物、及时发现并处理治疗过程中的药物不良反应、同时治疗糖尿病并发症是提高MDR-PTB并发糖尿病患者治疗成功率的关键。

关键词: 结核, 抗多种药物性, 糖尿病, 共病现象, 疾病特征, 临床方案, 综述文献(主题)

Abstract:

With the increasing prevalence of diabetes mellitus (DM) and multidrug-resistant pulmonary tuberculosis (MDR-PTB), the effect of DM on MDR-PTB has aroused people’s concern. The authors analyzed the effects of DM on MDR-PTB by summarizing the incidence, clinical features, imaging features, other bacterial infections, selection and application of anti-tuberculosis drugs, and treatment outcome of MDR-PTB patients complicated with DM in the domestic and foreign literatures. The results suggest that DM is an important risk factor for MDR-PTB. Effective control of blood glucose as soon as possible, reasonable selection of effective anti-tuberculosis drugs, timely detection and management of adverse drug reactions during treatment, and treatment of DM complications are the key to improve the success rate of MDR-PTB with diabetes.

Key words: Tuberculosis, multidrug-resistant, Diabetes mellitus, Comorbidity, Disease attributes, Clinical protocols, Review literature as topic

金龙,胡卫华,卢水华. 糖尿病对耐多药肺结核的影响与对策[J]. 中国防痨杂志, 2018, 40(9): 999-1002. doi: 10.3969/j.issn.1000-6621.2018.09.018

Long JIN,Wei-hua HU,Shui-hua LU. Effect of diabetes mellitus on multidrug-resistant pulmonary tuberculosis and the countermeasures[J]. Chinese Journal of Antituberculosis, 2018, 40(9): 999-1002. doi: 10.3969/j.issn.1000-6621.2018.09.018

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