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中国防痨杂志 ›› 2022, Vol. 44 ›› Issue (10): 1043-1049.doi: 10.19982/j.issn.1000-6621.20220251

• 论著 • 上一篇    下一篇

结核病和结核病/艾滋病病毒双重感染的负担与挑战:尼日利亚的案例研究

赵雅欣1, Olabi Onikepe2, 周忠良3(), 魏晓林4()   

  1. 1西安交通大学医学部公共卫生学院,西安 710061
    2重要战略公共卫生项目部,纽约 10005
    3西安交通大学公共政策与管理学院,西安 710049
    4多伦多大学达拉拉纳公共卫生学院,多伦多 M5T 3M7
  • 收稿日期:2022-07-08 出版日期:2022-10-10 发布日期:2022-09-30
  • 通信作者: 周忠良,魏晓林 E-mail:xiaolin.wei@utoronto.ca;zzliang1981@163.com

Burden and challenge of TB and TB/HIV co-infection: a case study of Nigeria

Zhao Yaxin1, Olabi Onikepe2, Zhou Zhongliang3(), Wei Xiaolin4()   

  1. 1School of Public Health, Health Science Center, Xi’an Jiaotong University, Shaanxi, Xi’an 710061, China
    2Department-Public Health Programs, Vital Strategies, NY 10005, USA
    3School of Public Policy and Administration, Xi’an Jiaotong University, Shaanxi, Xi’an 710049, China
    44Dalla Lana School of Public Health, University of Toronto, M5T 3M7, Canada
  • Received:2022-07-08 Online:2022-10-10 Published:2022-09-30
  • Contact: Zhou Zhongliang,Wei Xiaolin E-mail:xiaolin.wei@utoronto.ca;zzliang1981@163.com

摘要:

目的: 了解尼日利亚结核病与结核病/艾滋病病毒(TB/HIV)双重感染的负担和结核病综合防治措施的落实情况,以确定尼日利亚结核病防控所面临的挑战,为尼日利亚消除结核病提供参考依据。方法: 利用2010—2020年世界卫生组织的全球结核病报告数据描述尼日利亚的结核病与TB/HIV双重感染负担趋势。结果: 尼日利亚是结核病与TB/HIV双重感染高负担国家,HIV感染者结核病发病率从2010年的54/10万下降至2020年的17/10万;2020年结核病确诊患者数为13.5万例,估计发病例数为45.2万,结核病治疗覆盖率仅为30%;TB/HIV双重感染患者抗逆转录病毒治疗覆盖率从2010年的6.9%增加至2020年的26.0%;结核病成功治疗率从2010年的81%提高至2019年的88%,TB/HIV双重感染患者成功治疗率从2012年的78.9%提高至2019年的81.1%;尼日利亚结核病资金总量增加,TB/HIV项目资金变化小,从2010年的450万美元增长至2020年的540万美元。结论: 尼日利亚与2020年“终止结核病战略”的目标有很大的差距。尼日利亚要减轻并消除结核病和TB/HIV双重感染负担,必须优先考虑落实结核病综合防治措施,增加必要的结核病防治资源和经费,提高结核病诊断能力。

关键词: 结核, TB/HIV双重感染, 负担, 尼日利亚

Abstract:

Objective: To explore the burden of tuberculosis (TB) and TB/HIV co-infection and the implementation of integrated TB control measures in Nigeria, to identify the challenge for TB control and to provide reference for TB elimination in Nigeria. Methods: The World Health Organization’s TB data between 2010 and 2020 were used to depict the trend of TB and TB/HIV burden in Nigeria. Results: Nigeria is a country with high burden of infection of tuberculosis and TB/HIV. The incidence rate of tuberculosis among HIV infected people decreased from 54/100000 in 2010 to 17/100000 in 2020; In 2020, the number of confirmed tuberculosis patients was 135000, and the estimated number of cases will be 452000, however, the detection rate of tuberculosis was only 30%. The antiretroviral treatment coverage rate of TB/HIV co-infection increased from 6.9% in 2010 to 26.0% in 2020; The successful treatment rate of tuberculosis increased from 81% in 2010 to 88% in 2019, and the successful treatment rate of TB/HIV double infection patients increased from 78.9% in 2012 to 81.1% in 2019. The total funds of tuberculosis in Nigeria increased, while the TB/HIV project funds little changed, from US $4.5 million in 2010 to US $5.4 million in 2020. Conclusion: The situation in Nigeria is far from the goal of the 2020 End TB Strategy. To reduce and eliminate the burden of TB and TB/HIV, priority must be given to implement integrated TB control measures, increasing necessary resources and funds for TB control, and strengthening diagnostic ability of TB.

Key words: Tuberculosis, TB/HIV co-infection, Burden, Nigeria

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