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中国防痨杂志 ›› 2003, Vol. 25 ›› Issue (4): 267-269.

• 论著 • 上一篇    下一篇

C反应蛋白在结核活动中的意义

曾林海;许家琏;陈守君;   

  1. 上海市肺科医院 上海 200433;
  • 出版日期:2003-04-10 发布日期:2003-11-03

The clinical function of C-reaction protein in the diagnosis of active-tuberculosis

ZENG Lin-hai,XU Jia-lian,CHEN Shou-jun.   

  1. Shanghai Pulmonology Hospital,Shanghai 200433
  • Online:2003-04-10 Published:2003-11-03

摘要: 目的 研究C反应蛋白 (CRP)在诊断活动性结核中的临床意义。方法 选取 2002年 3月至 6月住院诊断为活动性结核病人 120例 (分为合并感染组与非感染组)痰结核菌阳性组与痰结核菌阴性组))非活动性结核病人 40例 (为对照组))分析各组C反应蛋白及红细胞沉降率检查结果的差异性。结果 (1)合并感染组CRP值及红细胞沉降率值均显著高于非感染组 (P<0.01)。 (2)活动结核组CRP值显著高于对照组 (P<0.01))而两组红细胞沉降率值无显著差异 (P>0.05)。(3)非感染组及痰菌阴性组CRP值明显高于对照组 (P<0.05))而两者红细胞沉降率值统计学无显著差异 (P>0.05)。 (4)痰结核菌阳性组CRP值及红细胞沉降率值均稍高于痰结核菌阴性组)两者均统计学无显著差异 (P>0.05)。结论 C反应蛋白升高对诊断结核病活动性有参考意义且优于红细胞沉降率检测。

关键词: C反应蛋白, 红细胞沉降率, 结核

Abstract: Objective To study the clinical function of C-reaction in the diagnosis of active-tuberculosis.Methods 120 cases with active-tuberculosis in our hospital (from Mar.2002 to jun.2002) were divided into infection group and non-infection group,bacteriological positive group and bacteriological negative group .The control group included 20 cases with non -active tuberculosis.The Results of C-reaction protein (CRP) and erythrocyte sedimentation rate (ESR) in all groups were detected and compared.Results (1) The CRP and ESR in infection group were all higher than the non-infection group significantly(P<0.01) (2) The CRP of active-tuberculosis was higher than the control group significantly (p<0.01),while there was no significant difference of ESR in the two groups (P>0.05). (3)The CRP of the non-infection group and bacteriological negative was higher than the control group significantly (P<0.05),while there was no significant difference of ESR in the two groups(P>0.05). (4) The CRP and ESR in bacteriological-positive group were all higher than the bacteriological-negative ,but there was no significant difference in two groups.Conclusion The CRP was more positive and more significant than ESR in the diagnosis of active-tuberculosis.

Key words: C-reaction protein, Erythrocyte sedimentation rate, Tuberculosis