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中国防痨杂志 ›› 2010, Vol. 32 ›› Issue (1): 20-24.

• 论著 • 上一篇    下一篇

初治涂阳肺结核治愈后近期复发预测模型

伍小英, 谭守勇, 张晋昕, 梁敏青, 陈其琛, 刘国标温文沛, 梁国飞, 梁国添, 罗少霞   

  1. 广州市胸科医院; 中山大学公共卫生学院;
  • 出版日期:2010-01-20 发布日期:2010-01-20

The prediction model for short-term recurrence after cured in initial-smear-positive pulmonary tuberculosis

Wu Xiaoying,Tan Shouyong,Zhang Jinxin,Liang Minqing,Chen Qichen,Liu Guobiao,Wen Wenpei,Liang Guofei,Liang Guotian,Luo Shaoxia   

  1. Guangzhou Chest Hospital,Guangzhou 510095 China;2.School of Public Health,Sun Yat-sen University,Guangzhou 510080 China
  • Online:2010-01-20 Published:2010-01-20
  • Contact: Zhang Jinxin E-mail:zhjinx@mail.sysu.edu.cn

摘要: 目的 建立初治涂阳肺结核治愈后近期复发的预测模型。方法 采用前瞻性追踪研究方法 ,对2005年1月1日—2006年12月31日广州市初治涂阳肺结核治愈停药的3 293例患者进行2年随访研究,从临床因素、社会因素探讨影响初治涂阳肺结核治愈后复发的相关因素,建立近期复发的logistic回归模型。 结果初治涂阳肺结核治愈后细菌学复发率为4.6%。近期复发预测模型:logit P=-9.546+0.586X1+1.959X6+1.449X10+1.118X15+1.027X16+1.525X18+0.674X22+2.042X23,经评价预测效果较好。 结论 预测模型的建立为减少肺结核复发提供了科学循证依据,能为结核病疫情控制给予针对性指导。

关键词: 结核, 肺, 复发, 预测

Abstract: Objective To establish a prediction model of short-term recurrence of cured initial-smear-positive pulmonary tuberculosis.  Methods This research was a prospective longitudinal study. 3293 cured initial-smear-positive pulmonary tuberculosis cases from Jan.2005 to Dec. 2006 from Guangzhou City were followed-up for 2 years. Influencing factors of recurrence of cured initial-smear-positive pulmonary tuberculosis were explored from clinical and social aspects and a logistic regression model for prediction were developed.  Results The bacteriology recurrence rate is 4.6%. Short-term recurrence prediction model is logit P=-9.546+0.586X1+1.959X6+1.449X10+1.118X15+1.027X16+1.525X18+0.674X22+2.042X23 with good prediction Results .  Conclusion s The prediction model provided a scientific evidence-based basis to reduce the recurrence of tuberculosis and a targeted instruction for the control of tuberculosis epidemic.

Key words: tuberculosis, pulmonary, recurrence, forecasting