114初治涂阳肺结核患者血清结核抗体IgG应用价值的再探讨

中国防痨杂志 ›› 2010, Vol. 32 ›› Issue (2): 114-116.

114初治涂阳肺结核患者血清结核抗体IgG应用价值的再探讨

钟红剑, 刘腊香, 朱飞, 陈文胜, 文善适, 赵安贵

广东省深圳市宝安区慢性病防治院；广东省深圳市宝安区龙华人民医院；

出版日期:2010-02-20 发布日期:2010-02-20

Further discussion on clinical value of serum tuberculosis antibody IgG in the first-treated patients with smear-positive pulmonary tuberculosis

Zhong Hongjian,Liu Laxiang,Zhu Fei,Chen Wensheng,Wen Shanshi,Zhao Angui

1.Hospital for chronic diseases of Baoan Shenzhen,Shenzhen 518133,China;2.Longhua hospital of Baoan Shenzhen,Shenzhen 518100,China

Online:2010-02-20 Published:2010-02-20
Contact: ZhongHongjian E-mail:lalami888@sina.com

摘要/Abstract

摘要： 目的探讨初治肺结核患者血清结核抗体(TB-Ab)IgG检测的临床应用价值和其影响因素。方法回顾性调查1 911例初治涂阳肺结核患者血清TB-Ab IgG阳性率，并与同期涂阴患者健康人群进行对照；观察血清TB-Ab IgG阳性率与病灶范围大小，有无空洞，是否排菌及排菌量多少的关系，将所得数据作统计学处理；同时观察血清TB-Ab IgG与结核纯蛋白衍化物皮肤试验（PPD）二者之间有无相关性。结果初治涂阳肺结核患者血清结核抗体阳性率仅53.3％，初治涂阴者为20.5%，健康人群血清结核抗体阳性率0.4％；初治涂阳患者血清TB-Ab IgG的阳性率与病灶范围大小，空洞有无及排菌量多少均有密切关系。结论血清TB-Ab IgG检测在肺结核患者中的特异性和敏感性值得商榷，其临床应用和诊断价值有待进一步完善和提高。

关键词: 结核, 肺/免疫学, 抗体, 细菌, 免疫球蛋白G

Abstract: Objective To reexplore the clinical value and influencing factors of serum tuberculosis antibody(TB-Ab) IgG in the first-treated patients with smear-positive pulmonary tuberculosis(TB). Methods The positive rate of serum TB-Ab-IgG in 1 911 first-treated patients with smear-positive TB were analyzed retrospectively and were compared with healthy people of in the same period.The relationships between positive rate of serum TB-Ab-IgG and some clinical features including the size of lesion,cavity wi...

钟红剑, 刘腊香, 朱飞, 陈文胜, 文善适, 赵安贵. 114初治涂阳肺结核患者血清结核抗体IgG应用价值的再探讨[J]. 中国防痨杂志, 2010, 32(2): 114-116.

Zhong Hongjian,Liu Laxiang,Zhu Fei,Chen Wensheng,Wen Shanshi,Zhao Angui. Further discussion on clinical value of serum tuberculosis antibody IgG in the first-treated patients with smear-positive pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2010, 32(2): 114-116.

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