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中国防痨杂志 ›› 2008, Vol. 30 ›› Issue (4): 307-310.

• 论著 • 上一篇    下一篇

WHO新疆结核病耐药监测报告

贾卫;吴卫东;张伟;顾晓明;于静;阿依努尔;刘年强;陈鹏   

  1. 新疆维吾尔自治区疾病预防控制中心结核病控制中心 乌鲁木齐 830002
  • 出版日期:2008-04-10 发布日期:2011-11-03

The report of WHO drug resistance surveillance on tuberculosis,Xinjiang

Jia Wei,Zhang Wei,Wu Weidong,et al.   

  1. TB Control Centre of Xinjiang Uygur Autonomous Region disease prevention and control center,Urumqi 830002,China.
  • Online:2008-04-10 Published:2011-11-03

摘要: 目的监测结核分枝杆菌的耐药情况,获得初始耐药、获得性耐药及耐多药资料,评价新疆维吾尔自治区的结核病控制工作。方法采用整群抽样方法,在全区抽取30个县(市)作为监测点,对调查期间新登记的涂阳病人、以及根据入选标准纳入的复治涂阳病例进行痰分离培养。结果入选病例1 083例,总耐药率为26.4%(286/1 083),初始耐药率25.9%(251/969),获得性耐药率30.7%(35/114),耐多药率为4.6%(50/1 083)。结论新疆维吾尔自治区的结核分枝杆菌的耐药率依然较高,结核病控制工作不容忽视。

关键词: 结核, 耐药性, 监测

Abstract: Objectives To evaluate the magnitude and pattern of drug resistant tuberculosis in Xinjiang,and to assess TB control performance in the region. Methods Thirty clusters were randomly selected with cluster sampling method.According to case enroll criteria,all the new smear positive cases and retreated smear positive cases during the survey period were involved and their sputum were collected for culture. Results Drug susceptibility testing against INH,RFP,SM and EMB were performed in 1083 cases.The overall drug resistance,drug resistance among new cases and retreated smear positive cases were 26.4%,25.9% and 30.7%,and the multi-drug resistance rate was 4.6%. Conclusions The prevalence of drug resistant tuberculosis is rather high in Xinjiang,and the quality of TB control performance need to be strengthened.

Key words: tuberculosis, drug resistance, surveillance