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中国防痨杂志 ›› 2002, Vol. 24 ›› Issue (4): 200-202.

• 论著 • 上一篇    下一篇

胸液P-选择素检测对结核性与恶性胸腔积液鉴别意义的探讨

赵云峰;王英年;高岱清;张春玲;马学真;吴学玲;刘加洪;   

  1. 青岛大学医学院第二附院 青岛 266042;
  • 出版日期:2002-04-10 发布日期:2002-11-03

Significance of detecting P-selectin of pleural effusion in differentiating tuberculous and malignant pleural effusions

ZHAO Yun feng,WANG Ying nian,GAO Dai qing,et al.   

  1. The Second Affiliated Hospital of Qingdao University Medical College,Qingdao 266042
  • Online:2002-04-10 Published:2002-11-03

摘要: 目的 检测结核性及恶性胸腔积液患者胸液P-选择素水平,探讨其对鉴别良恶性疾病的意义。方法 采用酶联免疫吸附法(ELISA法)检测48例结核性胸液及50例恶性胸液P-选择素水平。结果 恶性胸液P-选择素水平(18.76±8.45μg/L)明显高于结核性胸液P-选择素(7.43±5.32μg/L)(P<0.01)。结论 测定胸液P-选择素水平有助于结核性及恶性胸液的鉴别。

关键词: P-选择素, 胸腔积液, 酶联免疫吸附试验

Abstract: Objective To explore the clinical significance of detecting P-selectin of pleural effusions in differentiating tuberculous and malignant diseases.Methods To detect the content of P-selectin in centrifuged supernatant of 48 cases with tuberculous pleural effusions and 50 cases with malignant pleural effusions by ELISA method.Results P-selectin of malignant pleural effusions (18.76±8.45μg/L) was distinctly higher than that of tuberculous pleural effusions (7.43±5.32μg/L) (P<0.01).Conclusion Detecting P-selectin of pleural effusion might be helpful for differentiating tuberculous and malignant diseases.

Key words: P-selectin, Pleural effusion, Enzyme-linked immunosorbent assay