实验室检测技术在肺结核活动性判断中的应用进展

doi:10.3969/j.issn.1000-6621.2020.06.016

摘要/Abstract

摘要：

我国肺结核疫情十分严峻,临床上确诊活动性肺结核的“金标准”是结核分枝杆菌病原学检查,但对病原学阴性肺结核活动性的判断存在困难。作者介绍了目前用于病原学阴性肺结核活动性判断的实验室评价指标,包括结核分枝杆菌抗原、炎性和急性期反应标志物、免疫学指标、血液转录标志物等,指出了目前实验室检测技术在肺结核活动性判断及临床应用中存在的问题,并对其未来发展进行了论述与展望。

关键词: 结核, 肺, 活动性判断, 实验室技术和方法, 综述文献(主题)

Abstract:

The epidemic situation of pulmonary tuberculosis in China is challenging. The pathogenic test of Mycobacterium tuberculosis is the “golden indicator” for the diagnosis of pulmonary tuberculosis, but the diagnosis becomes difficult when the test results are negative. This review introduces the current evaluation methods of laboratory tests for activity judgment of pulmonary tuberculosis, such as Mycobacterium tuberculosis antigens, inflammatory and acute-phase reaction markers, immunological indicators, and blood transcription markers; points out the problems of current laboratory tests for activity judgment and clinical implementation; and discusses its future development.

Key words: Tuberculosis, pulmonary, Activity judgment, Laboratory techniques and methods, Review literature as topic

付亮, 邓国防. 实验室检测技术在肺结核活动性判断中的应用进展[J]. 中国防痨杂志, 2020, 42(6): 626-629. doi: 10.3969/j.issn.1000-6621.2020.06.016

FU Liang, DENG Guo-fang. Review on the progress of laboratory tests for activity judgment of pulmonary tuberculosis[J]. Chinese Journal of Antituberculosis, 2020, 42(6): 626-629. doi: 10.3969/j.issn.1000-6621.2020.06.016

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