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中国防痨杂志 ›› 2020, Vol. 42 ›› Issue (4): 316-321.doi: 10.3969/j.issn.1000-6621.2020.04.004

• 专论 • 上一篇    下一篇

科学开展预防性治疗 加速遏制结核病进程

卢鹏,成君,路希维,刘二勇,周林(),陆伟()   

  1. 210009 南京,江苏省疾病预防控制中心慢性传染病防制所(卢鹏、陆伟);中国疾病预防控制中心结核病预防控制中心(成君、刘二勇、周林);大连市结核病医院(路希维)
  • 收稿日期:2020-01-06 出版日期:2020-04-10 发布日期:2020-04-07
  • 通信作者: 周林,陆伟 E-mail:zhoulin@chinacdc.cn;weiluxx@163.com
  • 基金资助:
    “十三五”国家科技重大专项(2018ZX10715002)

Scientific preventive treatment to accelerate the process of tuberculosis control

LU Peng,CHENG Jun,LU Xi-wei,LIU Er-yong,ZHOU Lin(),LU Wei()   

  1. *Department of Chronic Communicable Disease, Center for Disease Control and Prevention of Jiangsu Province,Nanjing 210009,China
  • Received:2020-01-06 Online:2020-04-10 Published:2020-04-07
  • Contact: Lin ZHOU,Wei LU E-mail:zhoulin@chinacdc.cn;weiluxx@163.com

摘要:

WHO提出在2035年终止结核病,但如果仅依靠早期发现并治愈结核病患者,要实现这一目标是不现实的。切断传播途径及保护易感人群等措施就显得尤为重要。中国有相当一部分人群是潜伏性结核感染者,不可能对所有感染者都进行预防性治疗。WHO推荐了开展结核分枝杆菌感染检测和预防性服药的人群,但考虑到中国的国情,WHO的建议并不完全适用于中国。因此,科学定位我国的结核分枝杆菌感染人群中的结核病高危人群,并积极地对其开展预防性服药,对加速降低和控制我国结核病疫情具有重要意义。

关键词: 结核, 潜伏性结核病, 抗生素预防, 人群监测, 干预性研究, 评论, 预防性治疗

Abstract:

World Health Organization (WHO) have set a grand goal of eliminating tuberculosis (TB) by 2035, however, it is unrealistic to achieve this only relying on the measure of early detection and cure TB patients. Measures such as cutting off transmission routes and protecting susceptible populations are particularly important. There are a large number of people in China who are potentially infected with TB, and it is impossible for all the people to receive the preventive treatment. WHO has recommended people to identify at-risk populations for latent tuberculosis infection testing and treatment, but considering China’s national conditions, WHO’s recommendations are not entirely applicable to China. Therefore, it is of great significance to identify high TB risk population scientifically among people infected with Mycobacterium tuberculosis in our country and carry out preventive treatment.

Key words: Tuberculosis, Latent tuberculosis, Antibiotic prophylaxis, Population Surveillance, Intervention studies, Comment, Preventive therapy