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Chinese Journal of Antituberculosis ›› 2021, Vol. 43 ›› Issue (9): 965-969.doi: 10.3969/j.issn.1000-6621.2021.09.018

• Review Articles • Previous Articles     Next Articles

Pharmacodynamic characteristics and interaction of new antituberculosis drugs

QI Xue-ting, LU Yu(), CHEN Xiao-you()   

  1. *Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumour Research Institute, Beijing 101149, China
  • Received:2021-04-15 Online:2021-09-10 Published:2021-09-07
  • Contact: LU Yu,CHEN Xiao-you E-mail:luyu4876@hotmail.com;chenxy1998@hotmail.com

Abstract:

Treatment of tuberculosis currently still relies on chemotherapy,however,there are multitude problems in the existing chemotherapy regimens, such as long treatment course, various adverse reactions, and suboptimal outcomes.There is an urgent need to exploit potent drug combinations to improve the treatment efficacy and shorten the course of treatment.Herein, the pharmacodynamic characteristics and interactions of novel anti-tuberculosis drugs launched in recent years,as well as those in the research stage, are briefly reviewed to provide reference for the research and development of anti-tuberculosis drugs and new drug combination regimens.

Key words: Mycobacterium tuberculosis, Auti-tuberculosis drugs, Drug therapy,combination, Review literature as topic