Abstract:

Active discovery and preventive treatment is the core measure of tuberculosis control of the global strategy for ending tuberculosis epidemic. China is one of the countries with high burden of tuberculosis in the world. For the goal of ending tuberculosis in the world, strengthening the active discovery of latent tuberculosis infection (LTBI), screening the close contacts of tuberculosis patients, and preventive treatment for the newly infected and immunocompromised LTBI populations are important measures to reduce the incidence of LTBI. However, there are still many doubts and disputes about the applicable objects, regimes and effect of preventive treatment now. New diagnostic techniques and preventive treatment methods are constantly studied and applied. In view of this, experts from Chinese Antituberculosis Association have compiled the Expert consensus on detection and preventive treatment of latent tuberculosis infection in high-risk population, and reviewed the principle and detection of LTBI, and objects of prevention treatment, diagnostic methods, chemical prevention and immunization prevention, to provide reference for Chinese tuberculosis control workers.

Key words: Mycobacterium tuberculosis, Infectious disease incubation period, Diagnosis, Protective agents, Consensus development conferences as topic