Application progress of Xpert MTB/RIF Ultra assay in tuberculosis diagnosis in children

doi:10.3969/j.issn.1000-6621.2021.08.017

Abstract

Abstract:

Accurate diagnosis of tuberculosis timely is challenging in children because of the nonspecific clinical manifestations, low load of Mycobacterium tuberculosis in specimens, and insensitive and time-consuming characteristics of traditional diagnostic methods. Xpert MTB/RIF Ultra (Xpert Ultra), a new generation assay of Xpert, is gradually attract the attention of researchers and clinicians due to its superior performance and shorter turnaround time. In this review, the application of Xpert Ultra technology in pediatric tuberculosis was summarized to provide assistant for the diagnosis and treatment.

Key words: Tuberculosis, Child, Diagnosis, Nucleic acid amplification techniques, Review literature as topic

WANG Ya-cui, SUN Lin, SHEN A-dong. Application progress of Xpert MTB/RIF Ultra assay in tuberculosis diagnosis in children[J]. Chinese Journal of Antituberculosis, 2021, 43(8): 843-846. doi: 10.3969/j.issn.1000-6621.2021.08.017

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