重视结核性脑膜炎的诊断和治疗

doi:10.3969/j.issn.1000-6621.2019.01.005

摘要/Abstract

摘要：

结核性脑膜炎是最严重的结核病类型。近年来,在诊断方面研究者探索了改良抗酸染色技术、分子生物学方法、头颅MRI和临床评分系统用于结核性脑膜炎的诊断;在治疗方面着重研究了氟喹诺酮类药物和高剂量利福平用于改善结核性脑膜炎预后的可行性,并且发现应用糖皮质激素能降低结核性脑膜炎患者的病死率。此外,耐药结核性脑膜炎也成为日益突出的临床问题,提示临床医生应重视耐药结核性脑膜炎的诊断与治疗。

关键词: 结核, 脑膜, 诊断, 综合疗法, 评论

Abstract:

Tuberculous meningitis is the most serious form of tuberculosis. In the past several years, scientists investigated modified Z-N stain, molecular method, brain MRI and clinical scoring system to improve diagnosis of tuberculous meningitis, and studied fluoroquinolone and high-dose rifampin to improve prognosis of this disease. It is clear that corticosteroid could reduce risk of death among patients with tuberculous meningitis. In addition, drug-resistant tuberculous meningitis has become a problem worthy of being noticed and clinicians should pay more attention to the treatment of the disease.

Key words: Tuberculosis, meningeal, Diagnosis, Combined modality therapy, Comment

段鸿飞. 重视结核性脑膜炎的诊断和治疗[J]. 中国防痨杂志, 2019, 41(1): 14-17. doi: 10.3969/j.issn.1000-6621.2019.01.005

Hong-fei DUAN. To pay more attention to diagnosis and treatment of tuberculous meningitis[J]. Chinese Journal of Antituberculosis, 2019, 41(1): 14-17. doi: 10.3969/j.issn.1000-6621.2019.01.005

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