关键词: 结核, 肺, 重叠感染, 门诊病人, 对比研究

Abstract:

Objective To understand the present situation of the pulmonary tuberculosis cases with pulmonary other infection (PTB&PIN), and to explore the patients’ clinical characteristics for PTB&PIN in TB clinic.Methods A retrospective analysis was carried out on 506 new bacteriological positive PTB patients with the complete clinical data from January 2015 to June 2016 in a TB prevention and treatment center in Yuexiu district of Guangzhou. The patients were divided into the infection group (n=200) and the control group (n=306), according to whether they had complicated pulmonary infection or not at the time of visit. SPSS 19.0 software was used for statistical analysis, the counting data were analyzed by Chi-square test, which was statistical significance with P<0.05.Results (1) Of the 506 patients with PTB, 200 cases (39.53%) were complicated with PIN. There were 24.50% (49/200) patients aged over 60 years in the infection group, which was significantly higher than that in the control group (16.01%, 49/306) (χ ²=6.583, P=0.037). (2) In the infection group, there were 83.00% (166/200) patients with cough or expectoration symptoms, which was same as 76.47% (234/306)(χ ²=3.510, P=0.319) in the control group. (3) And there were 49.00% (98/200) patients with the lung involvement over 3 lesions in the infection group, which was significantly higher than that in the control group (31.70%,97/306)(χ ²=6.965, P=0.008).(4) In the infected group, there were 42.50% (85/200) patients with cavities in the focus, which were significantly higher than that in the control group (26.80%, 82/306)(χ ²=13.487, P=0.000).Conclusion Among the new bacteriological positive PTB patients who combined with other pulmonary infections in the tuberculosis specialist outpatient clinic, the proportion of the elderly patients is higher. The pulmonary lesions are more extensive and often accompanied with cavity formation.

Key words: Tuberculosis, pulmonary, Superinfection, Outpatients, Comparative study