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中国防痨杂志 ›› 2018, Vol. 40 ›› Issue (1): 94-97.doi: 10.3969/j.issn.1000-6621.2018.01.021

• 论著 • 上一篇    下一篇

北京市通州区结核病患者发病部位的关联性研究

康万里,刘洋,唐神结,郑素华()   

  1. 101149 北京市结核病胸部肿瘤研究所 首都医科大学附属北京胸科医院流行病学研究室(康万里、刘洋、郑素华),结核病多学科诊疗中心(唐神结)
  • 收稿日期:2017-07-13 出版日期:2018-01-10 发布日期:2018-03-14
  • 基金资助:
    “十二五”国家科技重大专项(2012ZX10004701-003);通州区科学技术委员会资助(KJ2017CX054)

Study on the association of different sites of tuberculous lesion in inpatients with tuberculosis from Tongzhou District, Beijing

Wan-li KANG,Yang LIU,Shen-jie TANG,Su-hua. ZHENG()   

  1. Department of Epidemiolegy Researth Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University,Beijing 101149, China
  • Received:2017-07-13 Online:2018-01-10 Published:2018-03-14

摘要:

目的 研究北京市通州区结核病患者发病部位的关联性,为临床医师提供有关结核病患者的相关信息,为临床诊断和治疗决策提供帮助。方法 以北京市通州区2006—2015年在首都医科大学附属北京胸科医院所有住院的638例结核病患者为研究对象,采用回顾性调查方法,查阅患者的住院病历信息,设计统一的调查表,内容包括结核病住院患者的性别、年龄、结核患病部位等信息,对患者的相关信息进行录入、整理。应用关联分析中的Apriori法研究结核病患者发病部位的关联性。结果 638例结核病患者中共患39种不同发病部位的结核,涉及病变部位863处。同时患2个部位及以上结核病变的患者例数占总例数的27.6%(176/638)。 863处病变部位中,主要包括肺结核459处(53.2%),结核性胸膜炎145处(16.8%),腰椎结核46处(5.3%),淋巴结结核34处(3.9%),支气管结核25处(2.9%),胸椎结核21处(2.4%)等。依据置信度>10%建立关联,发现14条关联。结论 某区1/4的结核病患者同时患有2个部位及以上的结核病变,因此,在诊断1个发病部位结核病变的时候要考虑到其关联的其他部位发生结核的可能。

关键词: 结核, 算法, 数据说明, 统计, 关联分析

Abstract:

Objective To study the association of different kinds of tuberculous lesion in inpatients with tuberculosis from Tongzhou District of Beijing in order to provide information of tuberculosis for clinical physicians to decide diagnosis and treatment.Methods We analyzed retrospectively 638 inpatients admitted in Beijing Chest Hospital during 2006 to 2015. Questionnaire informaiton including sex, age, lesion kind were investigated and recorded from hospitalized records. The association of different kind of tuberculous lesion were analyzed using the Apriori algorithm of associated analysis.Results There were 39 kinds of tuberculous lesion involved in 863 sites in 638 inpatients with tuberculosis. The rates of 2 or more than 2 kinds of tuberculous lesion were 27.6% (176/638). Of 863 sites of tuberculous lesion, there were 459 (53.2%) sites in pulmonary tuberculosis, 145 (16.8%) sites in tuberculous pleurisy, 46 (5.3%) sites in lumbar tuberculosis,34 (3.9%) sites in tuberculous lymphadenitis,25 (2.9%) sites in endobronchial tuberculosis,21 (2.4%) sites in thoracic vertebrae tuberculosis. Fourteen associations were found when the confidence was set more than 10%.Conclusion About one fourth inpatients suffer from 2 or more than 2 kinds tuberculosis lesion in Tongzhou District of Beijing. When one kind tuberculosis is diagnosed, the other kind tuberculosis needs to be considered combination probably.

Key words: Tuberculosis, Algorithms, Data interpretation, statistical, Association analysis