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中国防痨杂志 ›› 2015, Vol. 37 ›› Issue (2): 178-182.doi: 10.3969/j.issn.1000-6621.2015.02.012

• 论著 • 上一篇    下一篇

肺结核球误诊为周围型肺癌及两者的CT表现分析

陈亮 钟球 刘文 覃杰 梁波涛 高翠南 周琳   

  1. 510630  广州,广东省结核病控制中心(陈亮、钟球、梁波涛、高翠南、周琳);广州市胸科医院(刘文);中山大学附属第三医院(覃杰)
  • 收稿日期:2014-11-09 出版日期:2015-02-10 发布日期:2015-03-21
  • 通信作者: 周琳 E-mail:gdtb_bg@163.vip.com
  • 基金资助:

    “十二五”国家科技重大专项(2012ZX10004-903)

Analysis of CT findings between tuberculoma misdiagnosed as peripheral lung cancer and peripheral lung cancer

CHEN Liang, ZHONG Qiu,LIU Wen,QIN Jie, LIANG Bo-tao, GAO Cui-nan, ZHOU Lin   

  1. Guangdong Center for Tuberculosis Control, Guangzhou 510630, China
  • Received:2014-11-09 Online:2015-02-10 Published:2015-03-21
  • Contact: ZHOU Lin E-mail:gdtb_bg@163.vip.com

摘要: 目的 探讨周围型肺癌与误诊为周围型肺癌的肺结核球的CT表现差异。 方法 收集2010年1月至2014年1月在广州中山大学附属第三医院进行手术治疗的468例周围型肺癌及58例CT误诊为周围型肺癌的肺结核球患者,两组患者均由手术病理确诊。对比分析两组患者病灶的大小、部位、形状、密度、增强扫描后的特点、边缘、有无卫星病灶及肺门纵隔肿大淋巴结等征象。采用SPSS 20.0软件进行统计学分析,若两组计量资料数据呈正态分布且方差齐性,组间比较采用独立样本t检验;计数资料数据采用χ2检验,P<0.05为差异有统计学意义。 结果 58例误诊的肺结核球和468例周围型肺癌患者的病灶平均直径分别为(3.37±1.23)cm、(3.52±1.37)cm,两者差异无统计学意义(t=1.32,P=0.32)。沙砾状钙化、边缘光滑及卫星病灶相对于周围型肺癌[分别为5.13%(24/468)、8.97%(42/468)、10.47%(49/468)]多见于被误诊为周围型肺癌的肺结核球[分别为27.59%(16/58)、15.52%(9/58)、48.28%(28/58)](χ2值分别为37.04、15.23、59.23,P值均<0.01)。病灶边缘毛糙及胸膜凹陷相对于被误诊为周围型肺癌的肺结核球[分别为84.48%(49/58)、8.62%(5/58)],多见于周围型肺癌[分别为91.03%(426/468)、25.00%(117/468)](χ2=15.23,P<0.01;χ2=7.77,P<0.01)。在58例误诊的肺结核球内,16例可见沙砾状钙化灶,其中13例CT报告未描述病灶内沙砾状钙化灶。58例肺结核球的手术及CT均可见卫星灶,但仅7例CT报告描述卫星病灶。 结论 沙砾状钙化、病灶边缘光滑及卫星病灶多见于被误诊为周围型肺癌的肺结核球,而病灶边缘毛糙及胸膜凹陷多见于周围型肺癌。

关键词: 结核, 肺/ 诊断, 结核瘤/诊断, 肺肿瘤, 体层摄影术, X线计算机, 误诊

Abstract: Objective To investigate CT findings of peripheral lung cancer and tuberculoma misdiagnosed as peripheral lung cancer.  Methods From January 2010 to January 2014, 468 patients with confirmed peripheral lung cancer and 58 patients misdiagnosed as peripheral lung cancer were enrolled in the third affiliated hospital of SUN Yat-sen University. The shape, density, features of enhancement, margin, adjacent lymph nodes and satellite lesions were analyzed retrospectively. The statistical software package SPSS version 20.0 for Windows was used for the statistical analysis. Differences were considered to be statistically significant when P<0.05. Results The mean diameter of tuberculoma (3.37±1.23 cm) was similar to that of peripheral lung cancer (3.52±1.37 cm) (t=1.32,P=0.32). Compared with peripheral lung cancer with gravel-like calcification, smooth edge and satellite lesions(5.13% (24/468), 8.97% (42/468), 10.47% (49/468), respectively) were more commonly found than those of tuberculoma (27.59% (16/58), 15.52% (9/58), 48.28% (28/58), respectively)(χ2=37.04,P<0.01;χ2=15.23,P<0.01;χ2=59.23,P<0.01). Rough edge and pleural indentation were more commonly seen in peripheral lung cancer (91.03%(426/468), 25.00%(117/468), respectively) than those of tuberculoma(84.48%(49/58),8.62%(5/58),respectively)(χ2=15.23,P<0.01;χ2=7.77,P<0.01).  Conclusion Gravel-like calcification, smooth edge and satellite lesions are more commonly found in tuberculoma misdiagnosed as peripheral lung cancer, while rough edge and pleural indentation are more commonly seen in peripheral lung cancer.

Key words: Tuberculosis, pulmonary/diagnosis, Tuberculoma/diagnosis, Lung neoplasms, Tomography, X-ray computed, Diagnostic errors