1 World Health Organization. The world Health Report : Making a difference [R]. 1999:1102 唐神结,肖和平.细胞因子网络与结核病[J].中华结核和呼吸杂志,2001,24(9):571-5733 Alamelu Raja. Immunology of tuberculosis [J], Indian Med Resl 2004,20:213-2324 Verreck FA, DeBoer T,Langenberg DM, et al. Human IL-23-producing typel macrophages promote butIL-10-producing type 2 macrophages subvert immunity to (myco) bacteria [J]. Proc Natl Acad Sci USA, 2004,107(13): 4560 — 45655 Nagabhushanam V,Solache A, Ting LM. et al. Innate inhibition of adaptive immunity: mycobacterium tuberculosis-induced IL-6 inhibits macro-phages responses to IFN-gamma [J]. J Immunol, 2003,171(9):4570-45776 柏雪莲,傅斌,刘克义.结核分枝杆菌感染中一些重要免疫细胞和细胞因子作用的研究进展[J].中闽防痨杂志,2006,28(3):178-1817 王钢.复冰.树突状细胞在动脉粥样硬化病程中的病现意义[J].心血管康复医学杂志,2007,16(2): 198—2008 Vankayalapati R, Klucar P. Wizel B, et al. NKcell regulate CD8 Tcell effector function in response to an intracellular pathogen [J]. J Immonol, 2004,172(1): 130-1379 Junqueira-Kipnis AP,Kipnis A,Jamieson A, et al. NK cells repond to pulmonary infection with mycobacterium tuberculosis,but play a mini-mal role in protection [J]. J Immunol,2003, 171(11): 6039-604510 ru.skabov EB. Lyadova IV, Kondratieva TK, et al. Nertrophil re-sponses to mycobacterium tuberculosis infection in genetically suscept ible and resistant mice [J]. Infect Immon,2005,73(3): 1744-175311 Wang J,Santosuosso M, Ngai P. Activation of CD8 T cells by myco-bacterial vaccination protects against pulmonary tuberculosis in the absence of CD4 T cells [J]. J Immunol, 2004, 173(7) :4590-459712 雷建平.正确认识CD8细胞在结核病免疫治疗效果评价中的意义[J].中华结核和呼吸杂志,2003,26(2): 11213 Bapi P, Andrew A t Ronald S,et al. Intestinal double-positive CD4 CD8 T cells are highly activated memory cells with an increased capacity to produce cytokines [J]. J. Immunol, 2006,36: 583-59214 蔡亮,朱乃硕.CD1家族在脂类抗原呈递中的作用[J].细胞与分子免疫学杂志,2002,18(6): 109-11215 Flgnn JL, Chun J, Triebold KJ, et al. An essential role for inter-feron in resistance to mycobacterium tuberculosis infection [J]. J Exp Med,1993,178(6): 2249 — 225416 李其林.白介素对预防尖锐湿疣复发的研究[J].中国皮肤性病学杂志,1998,12(5):28917 Lasco TM, Yamamoto T,Yoshimura T. Effect of Mycobacterium bovis BCG vaccination on Mycobacterium-specific cellular proliferation and tumor necrosis factor alpha production from distinct guinea pig leukocyte populations [J]. Infect Immun,2003,71(12):7035-704218 Price NM, Gilman RH,Uddin J , et al. Unopposed matrix metallo proteinase-9 expression in human tuberculous granuloma and the role of TNF-alpha-dependent monocyte networks [J]. JImmunol, 2003,171 (10) :5579-558619 Demissie A, Abebe M,Aseffa A,et al. Healthy individuals that control a latent infection with mycobacterium tuberculosis express high levels of ThI cytokines and the IL-4 antagonist IL4 delta2 [J]. J Immunol, 2004, 172(11): 6938-694320 Seah GT, Rook GA. IL-4 influence apoptosis of mycobacterium-reactive lymphocytes in the presence of TNF-alpha [J].JImmunol,2001,137(3): 1230 —123721 Leal IS, Smedegard B, Andersen P,et al. lnterleukin-6 and inter-leukin-12 participate in induction of a type 1 protective Tcell response during vaccination with a tuberculosis subunit vaccine [J]. Infect lmmun,1999,67(11): 5747 — 575422 Bernadette M, Saddners, Anthony A. lnterleukin-6 induces early gamma interferon production in the infected lung but is not required gener-ation of specific immunity to mycobacterium tuberculosis Infection [J], Infection and Immunity, 2000,68(6):3322 — 332623 De la Barrera S, Aleman M, Musella R,et al. IL-10 down regulate costimulatory molecule on mycobacterium tiberculosis pulsed macrophages and impair the lytic activity of CD4 and CD8 CTL in tuberculosis patients [J].Clin Exp Immunol,2004,138(1): 128-13824 Fortsch D,Rollinghoff M, Stenger S, et al. IL-10 converts human dendritic cells into macrophage-like cells with increased antibacterial activity against virulent Mycobacterium tuberculosis[J]. J Immunol,2000, 165(2) :978—98725 Chensue SW, Warmington K, Ruth JH , et al. Effect of slow release IL-12 and IL-10 on inflammation,local macrophage function and reginal lymphoid response during mycobacterial (Thl)and schistosmal(Th2) antigen-elicted pulmonary granuloma formation [J]. Inflamm Res,1997,46(3):86一9226 Sugawara I, Yamada H,Kaneko H, et al. Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice [J]. Infect Immun, 1999,67:2585-258927 Yamada G,Shijubo N, Shigehara K, et al. Increased levels of circulating interleukin-18 in patients with advanced tuberculosis[J]. Am J Respir Crit Care Med, 2000,161:1786-1789 |