962例复治涂阳肺结核化疗效果影响因素分析

中国防痨杂志 ›› 2008, Vol. 30 ›› Issue (4): 320-322.

962例复治涂阳肺结核化疗效果影响因素分析

尹建军；钟球；蒋莉；李建伟

广东省结核病防治研究所广州 510630

出版日期:2008-04-10 发布日期:2011-11-03

Analysis on the factors affected the results of 962 retreatment smear-positive pulmonary tuberculosis cases

Yin Jianjun,Zhong Qiu,Jiang Li,et al

Anti-tuberculosis Research Institute of Guangdong Province,Guangzhou 510630,China

Online:2008-04-10 Published:2011-11-03

摘要/Abstract

摘要： 目的探讨复治涂阳肺结核化疗效果的影响因素和预测模型。方法运用Logistic回归分析法对影响962例复治涂阳肺结核病例化疗效果的诸多因素进行回顾性分析。结果经Logistic回归分析,2个月末痰涂片、咯血或血痰、化疗方案、病人分类、X线病变范围等五个因素对复治涂阳肺结核病例化疗效果影响具有显著性(P<0.05),并据此5项因素构建化疗效果预测模型。结论通过预测模型及时发现复治涂阳肺结核化疗失败高风险病例,为控制耐药、耐多药结核病(MDR-TB)的流行提供了新思路。

关键词: 结核,肺/流行病学, 结核,肺/预防和控制

Abstract: Objective To explore the factors related to the Results of retreatment smear-positive pulmonary tuberculosis cases and establish predictive model. Methods Retrospectively analyze the chemotheraputic Results of 962 retreatment smear-positive pulmonary tuberculosis cases through Logistic Regression Analysis. Results The model can be established based on the five factors which affect the Results significantly(P<0.05): the result of sputum smear test after two months of treatment,hemoptysis or bloody sputum,chemotherapy regimens,category of patient,extent of disease on radiograph. Conclusion The predictive model will be helpful to detect the potential failure cases more timely and provide new idea for MDR-TB control.

Key words: pulmonary tuberculosis/epidemiology, pulmonary tuberculosis/prevention and control

尹建军,钟球,蒋莉,李建伟. 962例复治涂阳肺结核化疗效果影响因素分析[J]. 中国防痨杂志, 2008, 30(4): 320-322.

Yin Jianjun,Zhong Qiu,Jiang Li,et al. Analysis on the factors affected the results of 962 retreatment smear-positive pulmonary tuberculosis cases[J]. Chinese Journal of Antituberculosis, 2008, 30(4): 320-322.