广东省WHO结核病耐药监测研究

摘要/Abstract

摘要： objective Based on the Guidelines for Surveillance of Drug Resistance in Tuberculosis of WHO/IUATLD set up a system for surveillance of drug resisitance of pulmonay tuberculosis.To obtain the result on ini-tial and acquired drug resistance rate of pulmonary tuberculosis in Guangdong province of China.Methods 40 counties were selected randomly in 113 counties of Guangdong province.39 cases of the new smear positive of pul-monary tuberculosis were intaken continuously in every county,including retreatment smear positive,Identify type of strains of culture positive and test drug resistance of the four kinds of antituberulosis drugs.Result Total drug resistance rate is 19.6%.Initial resistance rate was 18%.acquired drug resistance was 33.7%.Conclusion By strict training,all staff have grasped the drug resistance monitor system, based on the Guidelines for Surveillance of Drug Resistance in Tuberculosis of WHO/IUATLD. The result proved the drug resistance level in Guangdong is higher than that of developped countries.So national TB control program should be strengthen.

关键词: 结核, 药物耐受性, 监测, 广东

Abstract: Objective According to the guidelines of WHO/IUATLD proposed a global drug resistance surveillance of tuberculosis project,to set up a system for surveillance of drug resistance of pulmonary tuberculosis.to obtain the result on initianl and acquired drug resistance rate of pulmonary tuberculosis in Guangdong province of China.Methods 40 centres were radomly selected,39 cases of the smear positive of pulmonary tuberculosis were intook continuously in each centre.all samples were isolated and cultured.the identification and in each centre.all samples were isolated and cultured.the identification and susceptibility test were done for the strians of culture positive.Results The frequency of initial drug resistance was 18%,acquired drug resistance was 33.7%.Conclusion The result proved that drug resistance rate is higher(18%)in Guangdong province.National TB Control Program should be strengthen.

Key words: Tuberculosis, Drug resistance, Surveillance, Guangdong

钟球,钱明,李建伟,陈启亮,卓文基,江勇,黄树智,陈燕梅,. 广东省WHO结核病耐药监测研究[J]. 中国防痨杂志, 2001, 23(1): 5-8.

ZHONG Qiu,QIAN Min,LI Jian wei,et al.. Study on drug resistance surveillance of tuberculosis in Guangdong province[J]. Chinese Journal of Antituberculosis, 2001, 23(1): 5-8.

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广东省WHO结核病耐药监测研究

Study on drug resistance surveillance of tuberculosis in Guangdong province

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