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中国防痨杂志 ›› 2010, Vol. 32 ›› Issue (12): 825-827.

• 论著 • 上一篇    下一篇

耐多药肺结核治疗的近期临床观察

王小平; 顾欣荣; 强福林; 徐张汉;   

  1. 江苏省南通市疾病预防控制中心;
  • 出版日期:2010-12-15 发布日期:2011-08-23
  • 基金资助:

    江苏省预防医学科研项目资助(Y2002009)

Clinical observation of treatment in multidrug resistant pulmonary tuberculosis

Wang Xiaoping; Gu Xinrong; Qiang Fulin; Xu Zhanghan.   

  1. Disease Control and Prevention Center of; Nantong Jiangsu Province 226007; China;
  • Online:2010-12-15 Published:2011-08-23

摘要: 目的分析耐多药肺结核患者采用3CDLfxPtoZ/9DLfxPtoZ方案治疗的近期临床效果。方法 2002年10月至2005年12月收治的100例耐多药肺结核患者,采用3CDLfxPtoZ/9DLfxPtoZ方案治疗,疗程中进行痰结核分枝杆菌检查和肝功能检查,疗程的3、6、9、12个月摄X线胸片。结果 100例完成疗程时痰菌转阴率88.0%,病灶吸收率94.0%,空洞闭合率88.6%。肝功能异常率12.0%,无1例因药物不良反应停药。结论对耐多药肺结核采用方3CDLfxPtoZ/9DLfxPtoZ方案,近期效果满意,药物不良反应轻微,但其确切效果尚需进一步评价。

关键词: 结核, 抗多种药物性/药物疗法, 临床方案

Abstract: Objective To evaluate the efficacy of 3CDLfxPtoZ/9DLfxPtoZ regimen for multidrug resistant tuberculosis cases.MethodsOne hundred cases who hospitalized from Oct.2002 to Dec.2005 with multidrug resistant tuberculosis were treated with 3CDLfxPtoZ/9DLfxPtoZ regimen.Sputum smear examination and liver function test were detected for every patient each month,and X-ray chest photographs were taken in the 3rd,6th,9th and 12th months during the course of treatment.Results All patients completed the treatment.The spu...

Key words: tuberculosis, multi drug-resistant/drug therapy, clinical protocols

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