关键词: 血管肉瘤, 肺肿瘤, 免疫组织化学

Abstract: Objective To review the clinical features, pathological characteristics, diagnosis and differential diagnosis and treatment of pulmonary angiosarcoma.  Methods The clinical data in 5 cases was retrospectively analyzed with a literature review.  Results The clinical symptoms of pulmonary angiosarcoma were chest pain、cough and emptysis. Multiple nodules and plaque may be seen on Chest CT.Microscopically,the tumor was composed of blood vessel endothelium cells with obvious dysplasia, many irregular blood vessels varied in size were inosculated each other and formed vascular web.The immunohistochemical Results showedpositive CD34、CD31 and vimentin positive in cases. Conclusion Pulmonary angiosarcoma is a rare and high malignant soft tumor with poor prognosis, the diagnosis mainly depends on pattology.It needs to be differential diagnosted with lung adenocarcinoma, pulmonary tuberculosis, and mycosis etc.

Key words: hemangiosarcoma, lung neoplasms, imunohistochemistry