关键词: 结核,胸膜/免疫学, T淋巴细胞亚群, 细胞黏附分子

Abstract: ObjectiveTo retrospectively study the local pleural immune and inflammatory responses of patients with tuberculous pleurisy. Methods Collecting the samples of blood and pleural effusion from 35 cases with tuberculous pleurisy,we determined different T cells number marked CD3,CD4,CD8 and ICAM-1,2,3,VCAM-1 above samples through flow cytometer,and compared the rate of T subtypes in blood with pleural effusion. Results There was a significant increase at rate of T cells marked CD3,CD4 and CD4/CD8 in pleural effusion compared with it in blood,while there was a significant decrease of T cell marked CD8,and there were no differences at the rate of T cells marked ICAM-1,2,3,VCAM-1.There was no change at those rates of T subset cells in patients with different interval duration from start of symptom to admission checks. Conclusion CD4 cells were main immune responding T cells.There was no variation in T cell expressing adhesion molecules.

Key words: Tuberculous pleurisy/immunology, T-lymphocyte subsets, Cell adhesion molecules