肺结核不同病情对呼吸阻抗的影响

中国防痨杂志 ›› 2000, Vol. 22 ›› Issue (4): 217-219.

肺结核不同病情对呼吸阻抗的影响

孙卫红；严美贞；吴忠；

福建省福州肺科医院 350008；

出版日期:2000-04-10 发布日期:2000-04-10

The effect of pulmonary tuberculosis in different states of seriousness on the respiratory impedance

SUN Wei-hong,YAN Mei-zhen,WU Zhong.

Fuzhou Pulmonology Hospital,Fuzhou 350008

Online:2000-04-10 Published:2000-04-10

摘要/Abstract

摘要： 目的　探讨肺结核不同病情对呼吸阻抗的影响,评价脉冲振荡法(IOS)测定肺结核患者呼吸阻抗的临床意义。方法观察比较肺结核轻度组60例、中度组48例、重度组40例和健康组30例的IOS各指标,148例肺结核患者IOS各指标与肺通气功能指标实测值作相关分析。结果肺结核各组随病情加重,共振频率(Fres),呼吸总阻抗(Zrs),总气道阻力(R₅),中心气道阻力(R₂₀),周边气道阻力(R₅-R₂₀)和周边弹性阻力(X₅的负值)逐渐增大,但与健康组比较,肺结核轻度组各项指标无差异(P>0.05),肺结核中度组除R₂₀外其余各项均有显著性差异(P<0.05),肺结核重度组各项均有显著性差异(P<0.01)。148例肺结核患者IOS各指标与肺通气功能指标相关分析显示:Fres、Zrs、R₅、R₂₀和R₅-R₂₀分别与肺通气功能各指标呈显著负相关(P<0.001),X5与肺通气功能各指标呈显著正相关(P<0.001);Fres与MVV相关性最强。结论肺结核不同病情对呼吸阻抗影响差异很大。IOS法测定呼吸阻抗在肺结核临床应用中前景宽广。

关键词: 结核,肺, 呼吸阻抗, 脉冲振荡

Abstract: Objective To discuss the effect of pulmonary tuberculosis (PTB) in different states of illness on the respiratory impedance and evaluate the clinical significance of impulse oscillation(IOS) to determine the impedance in the patients with PTB.Methods The IOS indices of 60 patients with minimal PTB,48 cases of moderate advanced PTB,40 cases of far advanced PTB and 30 normal cases were compared with each other.Linear correlation was used to analyze the relationship between the impedance and ventilation indices of 148 cases.ResultsResonance frequenc frequency (Fres)、the total impedance(Zrs)、the total airway resistance(R₅)、the central airway resistance(R₂₀)、the peripheral airway resistance(R₅-R₂₀)and the peripheral capucitance(X₅) in the groups of PTB rose gradually with increasing of the seriousness of PTB.Compared with normal cases,the IOS indices of the patients with minimal PTB do not rose obviously(P>0.05).The IOS indices except R₂₀ rose obviously(P0.05)in the patients with moderate advanced PTB.The IOS indices of the patients with far advanced PTB rose obviously(P0.01).The negative correlation was found between IOS indices with the exception of X₅ and ventilation indices.The positive correlation was found between X₅ and ventilation indices.The correlation relationship between Fres and MVV are strongest in all.Conclusion The differences of effect in the patients with PTB on the impedance are very great.The applied foreground of IOS in the clinical PTB will be good.

Key words: Tuberculosis,pulmonary, Respiratory impedance, Impulse oscillation

孙卫红,严美贞,吴忠,. 肺结核不同病情对呼吸阻抗的影响[J]. 中国防痨杂志, 2000, 22(4): 217-219.

SUN Wei-hong,YAN Mei-zhen,WU Zhong.. The effect of pulmonary tuberculosis in different states of seriousness on the respiratory impedance[J]. Chinese Journal of Antituberculosis, 2000, 22(4): 217-219.