环丙氟哌酸治疗多耐药肺结核近远期疗效的观察

中国防痨杂志 ›› 1999, Vol. 21 ›› Issue (2): 87-88.

环丙氟哌酸治疗多耐药肺结核近远期疗效的观察

唐神结；潘金凤；黄彩柳；刘银开；林志新；翟康；汪正文；汪子书；

铜陵市第二人民医院;

收稿日期:1997-09-04 修回日期:1998-06-17 出版日期:1999-02-10 发布日期:1999-02-10

Observation of therapeutic effects of ciprofloxacin on multidrug resistant pulmonary tuberculosis patients

Tang Shenjie,Pan Jinfeng,Huang Cailiu, et al.

The Second People's Hospital of Tong Ling,Anhui 244000

Received:1997-09-04 Revised:1998-06-17 Online:1999-02-10 Published:1999-02-10

摘要/Abstract

摘要： 目的评价环丙氟哌酸(CPFX)对多耐药肺结核(MDR-PTB)的近远期疗效?方法51例MDR PTB患者分为两组:26例应用6CHETHT/6CHTHT方案治疗,25例采用6HETHT/6HTHT方案治疗?结果疗程结束时,治疗组痰菌阴转率(76.9%)明显高于对照组(28.0%)(P<0.01);经三年随访,治疗组和对照组细菌学复发率分别为10.0%和57.1%,两组间差异有显著性(P<0.05)?结论CPEX是治疗MDR-PTB的较为有效的药物?

关键词: 结核.肺, 多耐药, 环丙氟哌酸

Abstract: Objective To evaluate the effect of chemotherapy with ciprofloxacin on multidrug resistant pulmonary tuberculosis(MDR PTB).Method 51 cases with MDR PTB were allocated at random to two groups.26 cases were treated with the regimen of 6 CHETHT/6CHETHT.25 cases were treated with the regimen of 6HETHT/6HTHT.Result At the end of treatment,the rates of sputum negative conversion in the treatment group(76.9%) were higher than that in the control group(28.0%)( P<0.01).During three year follow up,the bacteriological relapase rates were found to be 10.0% in treatment group and 57.1% in control group.Comparing the two groups,there was an obvious difference( P<0 05).Conclusion CPFX was an effective drugs in treating patients with MDR PTB.

Key words: Tuberculosis, pulmonary, Multidrug resistant, Ciprofloxacin

唐神结, 潘金凤, 黄彩柳, 刘银开, 林志新, 翟康, 汪正文, 汪子书, . 环丙氟哌酸治疗多耐药肺结核近远期疗效的观察[J]. 中国防痨杂志, 1999, 21(2): 87-88.

Tang Shenjie,Pan Jinfeng,Huang Cailiu, et al.. Observation of therapeutic effects of ciprofloxacin on multidrug resistant pulmonary tuberculosis patients[J]. Chinese Journal of Antituberculosis, 1999, 21(2): 87-88.

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