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Chinese Journal of Antituberculosis ›› 1999, Vol. 21 ›› Issue (1): 37-38.

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Evaluation of Tb NT P BSA antigen in the serodiagnosis of tuberculosis

Hou Wei,Wu Qinxue,Yu Hua,et al.   

  1. Institute of Dermatology,Chinese Academy of Medical Science and Peking Union Medical College,Nanjing 210042
  • Received:1998-06-09 Revised:1998-11-17 Online:1999-01-10 Published:1999-01-10

Abstract: Objective To evaluate of Tb NT P BSA antigen in the diagnosis of tuberculosis.Method Sera from 40 tuberculosis cases and 52 healthy controls were assayed by ELISA using Tb NT P BSA(containing the terminal triglycosyl unit of the M.tuberculosis phenolic glycolipid) as antigen.Results The sensitivity and specificity were 94.2%,20.0% for IgG and 79.6%,45.0% for IgM antibody activity respectively.Conclusion This antigen is not sensitive,that will limit its use in the serodiagnosis of tuberculosis.

Key words: Tb NT P BSA, Serodiagnosis, Tuberculosis