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中国防痨杂志 ›› 2025, Vol. 47 ›› Issue (9): 1135-1139.doi: 10.19982/j.issn.1000-6621.20250305

• 专题笔谈 • 上一篇    下一篇

无症状结核病的隐匿传播与防控策略迭新

高磊1, 成诗明1, 金奇2(), 刘剑君1()   

  1. 1中国防痨协会,北京 100710
    2中国医学科学院病原生物学研究所,北京 102629
  • 收稿日期:2025-07-28 出版日期:2025-09-10 发布日期:2025-08-27
  • 通信作者: 金奇,刘剑君 E-mail:jinqi@ipbcams.ac.cn;liujj@chinacdc.cn
  • 基金资助:
    国家自然科学基金面上项目(82473697)

Occult transmission of asymptomatic tuberculosis and iterative renewal of prevention and control strategies

Gao Lei1, Cheng Shiming1, Jin Qi2(), Liu Jianjun1()   

  1. 1Chinese Antituberculosis Association, Beijing 100710, China
    2Institute of Pathogen Biology, Chinese Academy of Medical Sciences, Beijing 102629, China
  • Received:2025-07-28 Online:2025-09-10 Published:2025-08-27
  • Contact: Jin Qi,Liu Jianjun E-mail:jinqi@ipbcams.ac.cn;liujj@chinacdc.cn
  • Supported by:
    National Natural Science Foundation of China(82473697)

摘要:

无症状结核病(asymptomatic tuberculosis,aTB)患者作为结核病防控目标人群中的特殊群体,由于其病情隐匿性强、临床诊断难度大等特点,给全球结核病防控工作带来了重大挑战。本文基于世界卫生组织最新定义,结合相关研究进展及全球aTB流行病学证据,构建“问题界定-影响评估-策略创新-挑战应对”的逻辑框架,系统阐述aTB在疾病谱重构中的关键作用,以及其对筛查策略、临床诊治和公共卫生管理的深层影响,以期为优化aTB的防控策略提供理论依据和实践参考。

关键词: 结核, 无症状结核病, 传染病控制, 疾病管理, 总结性报告

Abstract:

As a special target population in tuberculosis (TB) prevention and control, patients with asymptomatic tuberculosis (aTB) pose significant challenges to global TB control efforts due to the strong concealment of their condition and the difficulty in clinical diagnosis. Based on the latest definition by the World Health Organization and combined with relevant research progress and global epidemiological evidence on aTB, this paper constructs a logical framework of “problem definition-impact assessment-strategy innovation-challenge response” to systematically elaborate on the key role of aTB in the reconstruction of the disease spectrum, as well as its in-depth impacts on screening strategies, clinical diagnosis and treatment, and public health management. It is expected to provide theoretical basis and practical reference for optimizing aTB prevention and control strategies.

Key words: Tuberculosis, Asymptomatic tuberculosis, Communicable disease control, Disease management, Consensus development conference

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