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中国防痨杂志 ›› 2009, Vol. 31 ›› Issue (3): 121-125.

• 论著 •    下一篇

江苏省2006年结核病流行病学抽样调查结果分析

陆伟;周扬;范本达;章体慧;杨丹丹;虞浩;陈宗兰;许卫国   

  1. 江苏省疾病预防控制中心南京 210009
  • 出版日期:2009-03-10 发布日期:2011-11-03

Analysis of sample survey for the epidemiology of tuberculosis in Jiangsu province in 2006

Lu Wei, Zhou Yang, Fan Benda, Zhang Tihui, Yang Dandan, Yu Hao, Chen Zonglan, Xu Weiguo   

  1. Jiangsu Center for Disease Control amd Prevention, Nanjing 210009, China
  • Online:2009-03-10 Published:2011-11-03

摘要: 目的了解目前江苏省结核病患病情况及流行特征,分析全省结核病流行变化趋势。方法采取分层整群抽样的方法, 计算得出全省流调点40个,抽样比例为1∶1203。对抽样点的所有人群进行登记造册,满15周岁以上无肺结核可疑症状的应检人口,均进行X线透视检查,不满15岁的儿童均作PPD检查,透视和PPD检查结果异常者及具有肺结核可疑症状的应检人口均进行X线摄片检查、3次痰涂片检查和2次痰结核菌培养检查。 结果江苏省2006全省活动性肺结核患病率282.47/10万,涂阳肺结核患病率为58.11/10万,菌阳肺结核患病率为79.09/10万,与1990年全省流调结果相比,涂阳患病率下降了54.3%,肺结核死亡专率为2.2/10万,比1990年下降了85.4%。30岁及以上年龄组男性患病率均高于女性,且差异随年龄的增长逐渐扩大。农村和城镇的结核菌感染率分别为5.3%和1.5%。流动人口主要年龄段的患病率显著高于相应年龄段的本地人口。流调已知的活动性肺结核病人占活动性病人的55.4%,其接受治疗率为99%,其中全程督导和全程管理占88.5%。有症状未就诊者中90.1%是中老年患者。结论通过实施《全国结核病防治规划(2001—2010年)》,采取多种有效措施,江苏省结核病疫情有大幅度下降,涂阳肺结核患病率,死亡率与1990年相比下降明显。但结核病疫情的总体水平仍然较高,特别是老年人肺结核发病率高且发现率较低,应引起高度重视。流动人口大幅度增加,提示在今后的全国性流调中,一定要事先充分考虑抽样方法和实施方法的问题,对涂阴病人的诊断应跟踪随访确诊等。

关键词: 结核,肺/流行病学, 结核,肺/预防和控制, 抽样研究, 江苏省

Abstract: ObjectiveTo realize the epidemical situation of pulmonary tuberculosis (PTB) in Jiangsu province and analyze the tendency of the epidemic variation. MethodsWith stratified cluster sampling method, a total of 40 investigation points was sampled and the sampling proportion was 1∶1203. All population in the investigation points was registered. Chest X-ray was applied to all population ≥15 years old without PTB symptom, PPD test was carried out among the children younger than 15 years old. Chest X-ray, 3 sputum direct smears and 2 cultural examinations were applied to all people with PTB symptom and all people with abnormal result of chest X-ray and PPD test. ResultsThe prevalence rate of active TB, smear positive and bacteriological confirmed PTB were 282.47/100000, 58.11/100000 and 79.09/100000 respectively. The prevalence rate of smear positive TB had a 54.3% declining compared with the rate of 1990. The mortality rate of PTB was 2.2/100000, and had an 85.4% declining compared with 1990. In the age groups of 30-year and above, male’s prevalence rate was higher than female’s and the difference expanded gradually with the age increased. The infection rates of tuberculosis were 5.3% in rural area and 1.5% in urban region. In the main age groups, the prevalence rate of migrant population was higher obviously than local resident’s. The proportion of the active PTB cases in all active cases was 55.4%, of which 99% received treatment, the proportion of active PTB cases treated under DOT and management was 88.5%. 90.1% non-consultation cases with symptoms were middle and old age people. ConclusionsThrough the implementation of The National Tuberculosis Control Program (2001—2010) and various effective measures, smear positive prevalence rate and mortality rate had declined sharply compared with the rates of 1990. But the tuberculosis epidemical situation is still serious, especially in aged people, which had a high prevalence rate and a low detection rate. With the rapid increasing of migrant population, the sampling method and implementation should be considered sufficiently in national survey in future. In addition, the diagnosis of smear-negative cases, should be further confirmed during follow-up visit.

Key words: pulmonary tuberculosis/epidemiology, pulmonary/prevention and control, sampling studies, Jiangsu province