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Chinese Journal of Antituberculosis ›› 2023, Vol. 45 ›› Issue (3): 253-259.doi: 10.19982/j.issn.1000-6621.20220391

• Special Topic • Previous Articles     Next Articles

Differential diagnosis between latent tuberculosis infection and active tuberculosis

Xia Hui1, Wang Ruibai2(), Zhao Yanlin1   

  1. 1National Tuberculosis Reference Laboratory, National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
    2Tuberculosis Department, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
  • Received:2022-10-09 Online:2023-03-10 Published:2023-03-07
  • Contact: Wang Ruibai E-mail:wangruibai@icdc.cn

Abstract:

China is a country with a high burden of tuberculosis and latent tuberculosis infection. The treatment and prognosis of latent tuberculosis infection and active tuberculosis are completely different. The current available diagnostic tools for tuberculosis infection cannot effectively predict the progress of infection and differentiate it from active tuberculosis, therefore, more accurate biomarkers need to be developed. The research progress, challenges and prospects of biomarkers for differential diagnosis between latent tuberculosis infection and active tuberculosis were reviewed in the present study.

Key words: Mycobacterium tuberculosis, Infection, Biological markers, Diagnosis, differential, Consensus development conferences as topic

CLC Number: