Value of PET-CT in the evaluation of pulmonary tuberculosis activity

doi:10.19982/j.issn.1000-6621.20210712

Abstract

Abstract:

Imaging plays an important role in the evaluation of tuberculosis activity. ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) PET-CT provides both metabolic and morphology information of tuberculosis. ¹⁸F-FDG-PET-CT can indicate the degree of glucose metabolism of cells, which could be used to comprehensively evaluate the activity of tuberculosis combined with morphological features. ¹⁸F-FDG-PET-CT may identify subclinical pulmonary tuberculosis in patients with latent tuberculosis infection. Patients with obsolete pulmonary tuberculosis without ¹⁸F-FDG uptake have low risk of recurrence. ¹⁸F-FDG-PET-CT can early evaluate the effect of anti-tuberculosis treatment, the decrease of standard uptake value (SUV) indicates effective treatment, and no ¹⁸F-FDG uptake may indicate that the Mycobacterium tuberculosis have been killed because of the treatment. ¹⁸F-FDG PET-CT may be used as an examination method to evaluate the efficacy of new anti-tuberculosis drugs and determine the endpoint of treatment time. This paper reviews the application and value of ¹⁸F-FDG PET-CT in identifying latent tuberculosis infection and evaluating the efficacy and prognosis of anti-tuberculous therapy in tuberculosis patients.

Key words: Positron-emission tomography, Tomography,emission-computed, Tuberculosis,pulmonary, Diagnosis,differential, Review

CLC Number:

R81
R521

LI Duo, LYU Ping-xin. Value of PET-CT in the evaluation of pulmonary tuberculosis activity[J]. Chinese Journal of Antituberculosis, 2022, 44(4): 409-411. doi: 10.19982/j.issn.1000-6621.20210712

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