Attention should be paid to the research and development of Mycobacterium tuberculosis antigen detection technology

doi:10.19982/j.issn.1000-6621.20210558

Abstract

Abstract:

New fast and convenient early screening or diagnosis technologies are required because of new situation of tuberculosis epidemic prevention and control. Simple, fast and cheap immunological diagnosis technology is the focus and persistent efforts of tuberculosis researchers. At present, the antigen targets of Mycobacterium tuberculosis (MTB) include the detection of single antigen and the simultaneous detection of multiple antigens. The involved detection technologies include immunological technology, mass spectrometry technology and nanotechnology. With the development of technology, great progress has been made in detection technology and research ideas of MTB antigen. However, there are still some problems. The simultaneous detection of multiple specific antigens should be deeply developed in research of MTB antigen. The development of new nanomaterials and sensing methods, as well as the discovery and research of antigens with strong specificity and good immunogenicity, are help to get new improvement and development of MTB antigen detection method.

Key words: Mycobacterium tuberculosis, Antigens, Diagnostic techniques and procedures, Consensus development conferences as topic

CLC Number:

R378.91
R392

SUN Zhao-gang. Attention should be paid to the research and development of Mycobacterium tuberculosis antigen detection technology[J]. Chinese Journal of Antituberculosis, 2022, 44(2): 120-124. doi: 10.19982/j.issn.1000-6621.20210558

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