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中国防痨杂志 ›› 2015, Vol. 37 ›› Issue (3): 237-242.doi: 10.3969/j.issn.1000-6621.2015.03.004

• 论著 • 上一篇    下一篇

脊柱结核伴截瘫的围手术期管理

范俊 秦世炳 董伟杰 兰汀隆 徐双铮   

  1. 101149  首都医科大学附属北京胸科医院骨科
  • 收稿日期:2014-11-19 出版日期:2015-03-10 发布日期:2015-04-03
  • 通信作者: 秦世炳 E-mail:qinsb@sina.com
  • 基金资助:

    北京市科技计划课题(D141107005214002)

Perioperative management of spinal tuberculosis with paraplegia

FAN Jun, QIN Shi-bing, DONG Wei-jie, LAN Ting-long, XU Shuang-zheng   

  1. Department of Orthopedics, Beijing Chest Hospital, Capital Medical University; Beijing Treatment Center for Bone and Joint Tuberculosis, Beijing 101149, China
  • Received:2014-11-19 Online:2015-03-10 Published:2015-04-03
  • Contact: QIN Shi-bing E-mail:qinsb@sina.com

摘要: 目的 探讨就诊脊柱结核合并截瘫的围手术期的管理经验。 方法 回顾性分析2009年1月至2014年10月在北京胸科医院骨科住院治疗的183例脊柱结核伴截瘫患者的临床住院资料。其中男76例,女107例。年龄2~87岁,平均年龄(52.2±17.2)岁。总结围手术期合并症、并发症及其相应积极的处置方法和手术疗效。采用SPSS 17.0软件对患者手术前后神经功能情况、疼痛度及脊柱后凸角度的资料进行统计学分析,计量资料两组间比较采用t检验,P<0.05为差异有统计学意义。 结果 术前有合并症者140例,主要包括肺结核(65例)、糖尿病(31例)、高血压(24例)等;术后常见的并发症为低蛋白血症(98例)、贫血(69例)、低钾血症(26例)、窦道形成(14例)、心功能不全(9例)、心律失常(6例)等。在采取相应的措施治疗后,患者均安全度过围手术期。围手术期内患者神经功能按美国脊柱损伤协会(ASIA)《脊髓损伤神经学分类标准(2011年版)》进行分级,164例患者较术前改善了1~2级。本组患者脊柱后凸畸形术后均得到矫正,术前Cobb角为(19.2±6.3)°,术后改变为(6.2±2.5)°,差异有统计学意义(t=6.956,P<0.05)。患者疼痛症状改善明显,按视觉模拟评分法(visual analogue scale,VAS)标准进行评分,由术前的(7.4±1.3)分改善为术后的(2.2±0.3)分,差异有统计学意义(t=8.964,P<0.05)。 结论 脊柱结核合并截瘫患者手术前合并症及术后并发症较多,积极的围手术期评估和正确处理是脊柱结核合并截瘫手术成功的重要保证。

关键词: 结核, 脊柱/外科学, 截瘫, 围手术期医护

Abstract: Objective  To investigate the experience in perioperative management of spinal tuberculosis with paraplegia. Methods A retrospective analysis was conducted. The clinical information from 183 patients with spinal tuberculosis and paraplegia who stayed and got treatment at Orthopedics Department of the Beijing Chest Hospital from January 2009 to October 2014 was analyzed, including complications during perioperative period and management methods, treatment outcomes of surgical operations. Among those patients, 76 cases were male and 107 cases were female; the average age was(52.2±17.2) years old (range 2-87 years). SPSS 17.0 software was used for statistic analysis of the data related to patients’ nerve function, degree of pain and angle of kyphosis before and after operation. The t-test was used for comparisons between two groups and P<0.05 was regarded as statistically significant difference. Results One hundred and forty patients out of 183 enrolled patients had preoperative complications, mainly including pulmonary tuberculosis (65 cases), diabetes (31 cases), high blood pressure (24 cases), etc.; after operations, the common postoperative complications in patients were hypoalbuminemia (98 cases), anemia (69 cases), hypokalemia (26 cases), sinus tract (14 cases), cardiac insufficiency (9 cases), arrhythmia (6 cases), etc. All patients safely passed the perioperative period under appropriate management. In the perioperative period, nerve function of the patients were evaluated according to the International Standards for Neurological Classification of Spinal Cord Injury (revised 2011) published by the American Spinal Injury Association (ASIA), and the results showed that the nerve function in 164 patients improved 1-2 levels. All patients’ kyphosis angles were corrected satisfactory from (19.2±6.3)° (preoperative Cobb Angle) to (6.2±2.5)° (postoperation Cobb angles), and it was a significantly deference (t=6.956, P<0.05). The pain was measured by using the visual analogue scale (VAS), and the results showed a significant decrease in pain scores from preoperative values of (7.4±1.3) points to postoperative values of (2.2±0.3) points (t=8.964, P<0.05).  Conclusion Spinal tuberculosis patients with paraplegia had more complications before and after surgical operations, so it is an important guarantee of successful operations to conduct correct assessments and appropriate management in those patients during perioperative period.

Key words: Tuberculosis, spinal/surgery, Paraplegia, Perioperative care