学校结核病暴发控制策略研究进展

摘要/Abstract

摘要： 结核病暴发是我国面临的严重校园公共卫生挑战之一。笔者对学校结核病疫情面临的挑战、现场流行病学调查，以及结核病暴发处置的相关问题进行了综述，重点概述了结核病潜伏感染的筛检手段与干预措施研究进展。归纳得出：肺结核患者早期发现是控制结核病暴发的基本手段；暴露关系与PPD试验相结合是评价结核潜伏感染的有效手段；预防治疗方案的短程化与全程管理是提高潜伏感染者治疗依从性的关键，等等，为制定科学的学校结核病防控技术策略提供参考。

关键词: 结核/预防和控制, 疾病暴发流行/预防和控制, 结核菌素试验, &, gamma, 干扰素释放试验

Abstract: Tuberculosis outbreak is one of serious public health challenges in schools in China. This article reviews challenges that tuberculosis control faces in school, field epidemiologic surveys and measures dealing with tuberculosis outbreaks. It summarizes particularly the research progress of screening tools and treatment of latent tuberculosis infection and concludes that early detection of pulmonary tuberculosis cases is the fundamental approach of tuberculosis outbreak control, combination of exposure with TST is an effective means to evaluate the latent tuberculosis infection, short-term chemotherapy and full administration are critical approaches to improve patient compliance. This article provides a reference for the development of scientific strategy on tuberculosis control in school.

Key words: Tuberculosis/prevention &, control, Disease outbreaks/prevention &, control, Tuberculin test, Interferon-gamma release tests

路希维. 学校结核病暴发控制策略研究进展[J]. 中国防痨杂志, 2013, 35(9): 752-756.

LU Xi-wei. Research progress of control strategy on tuberculosis outbreak in school[J]. Chinese Journal of Antituberculosis, 2013, 35(9): 752-756.

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