156例肺结核患者下呼吸道致病菌种鉴定及临床分析

中国防痨杂志 ›› 1999, Vol. 21 ›› Issue (3): 144-146.

156例肺结核患者下呼吸道致病菌种鉴定及临床分析

董志云；于森；杜云泽；夏俊娣；张文华；

天津肺科医院 300051；

收稿日期:1998-10-20 修回日期:1999-05-10 出版日期:1999-03-10 发布日期:1999-03-10

Pathogenic bacteria identify and clinical analysis of 156 caseswith pulm onary tuberculosis in lower respiratory tract

Dong Zhiyun , Yu Sen , Du Yunze ,et al .

Tianjin Lung Hospital , Tianjin 300051

Received:1998-10-20 Revised:1999-05-10 Online:1999-03-10 Published:1999-03-10

摘要/Abstract

摘要： 目的探讨肺结核患者下呼吸道致病菌种分布特点?细菌耐药情况及并发肺感染时临床特征?方法选156 例痰普通菌或真菌培养发现致病菌株的肺结核患者,确定菌种后进行抗菌药物体外药敏检测?结果 156 例患者痰细菌培养发现致病菌株239 例次?其中革兰氏阴性杆菌210 株(87.9 % ) ,真菌21 株(8.8 % ) ,革兰氏阳性球菌8 株(3.3 % ) ?药物敏感检测环丙沙星敏感菌株最高为60.6 % ,利福平最低为4.1 % ?结论肺结核患者呼吸道致病菌种以革兰氏阴性杆菌居多,可能与患者免疫功能低下?滥用抗生素及抗结核药物有关?

关键词: 结核,肺, 呼吸道, 致病菌

Abstract: Objective To investigate the characteristics of the distribution and drug resistant of pathogenicbacteria in lower respiratory tract of pulmonary tuberculosis cases ,and analyze the clinical manifestation w hen co m plicated with pneu monia . Methods 156 cases with pulmonary tuberculosis were taken for strain identification and sensi tivity test to antibiotic in vitro afterthe result positive of bacteria and fungus culture . Results All of 239 cases for pathogenicbacterialstrains were found in sputums bacterial culture of 156 patients. There were 210 strains of gram negative bacilli(87.9 % ) ；fungus were 21(8.8 % ) ；gram positive cocci were 8(3.3 % ) . The detection of drug sensitive test suggested thatciprofloxacin had the highest susceptibility ,rates was 60.6 % ,and rifampicin had thelowestsusceptibility ,only 4.1 % . Conclu sion The primary pathogenic bacteria were gram negative bacilliin lower respiratory tract of pulmonary tuberculosis patients . This may be related toim munodeficiency ,abuse antibiotic and treated with antituberculosis drugs .

Key words: Tuberculosis, pulm onary, Respiratory tract, Pathogenic bacteria

董志云, 于森, 杜云泽, 夏俊娣, 张文华, . 156例肺结核患者下呼吸道致病菌种鉴定及临床分析[J]. 中国防痨杂志, 1999, 21(3): 144-146.

Dong Zhiyun , Yu Sen , Du Yunze ,et al .. Pathogenic bacteria identify and clinical analysis of 156 caseswith pulm onary tuberculosis in lower respiratory tract[J]. Chinese Journal of Antituberculosis, 1999, 21(3): 144-146.

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