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中国防痨杂志 ›› 2005, Vol. 27 ›› Issue (5): 319-321.

• 论著 • 上一篇    下一篇

95例活动性肺结核免疫检测结果分析

李月翠1;黄晓东2;唐神结3;   

  1. 1.浙江永康第一人民医院;永康 321300;2.辽宁盘锦市结防所; 盘锦 124000;3.上海市肺科医院 上海 200433;
  • 出版日期:2005-05-10 发布日期:2005-11-03

Analysis on immunodetection results of 95 active pulmonary tuberculosis cases

Li Yuecui1,Huang Xiaodong,Tang Shenjie.   

  1. 1.Yongkang First People’s Hospital of Zhejiang Province,Yongkang 321300,China
  • Online:2005-05-10 Published:2005-11-03

摘要: 目的 探讨活动性肺结核患者体液免疫与细胞免疫之间的相关性。方法 对95例活动性肺结核患者进行血清T淋巴细胞亚群以及结核抗体的测定,同时做结核菌素纯蛋白衍生物(PPD)试验。结果 与阴性患者比较,痰菌阳性患者血清结核抗体及PPD试验的阳性率显著升高。而T细胞亚群变化与痰菌关系不大。血清结核抗体阳性者,T细胞亚群异常率升高。当PPD呈较强反应时,T细胞亚群正常的概率高。结论 T细胞亚群的检测能间接了解结核抗体及PPD试验的变化,反映机体的免疫状况。

关键词: 结核,肺, T淋巴细胞亚群, 结核抗体, 结核菌素试验

Abstract: Objective To assess the relation between cellular immunity and humoral immunity in active pulmonary tuberculosis patients.Method T lymphocyte subsets and tuberculous antibody were measured in serum of 95 cases of active pulmonary tuberculosis,and PPD tests were done in all patients.Results The positive rates of tuberculous antibody and PPD tests in patients with bacteriological positive pulmonary tuberculosis were higher than those in patients with bacteriological negative pulmonary tuberculosis.There was no significant relation between T lymphocyte subsets and sputum bacteriology.The abnormal rates of T lymphocyte subsets were high when tuberculous antibodys in serum were posiyive.The probability of nomal T lymphocyte subsets in serum were high when the positive rates of PPD tests were enhanced.Conclusion The detection of T lymphocyte subsets in serum in patients with pulmonary tuberculosis can indirectly understand the changes of tuberculous antibody and PPD tests,reflect immune status of organism.

Key words: Tuberculosis,pulmonary, T lymphocyte subsets, Tuberculous antibody, Tuberculin test