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中国防痨杂志 ›› 2009, Vol. 31 ›› Issue (12): 693-696.

• 论著 • 上一篇    下一篇

耐多药肺结核继发肺部真菌感染51例临床分析

叶梦华1;张忠顺2;杨妍2;刘轾彬2   

  1. 1.湖北省黄石市第二医院肺科 黄石 435002;2.同济大学附属上海肺科医院 上海 200433
  • 出版日期:2009-12-10 发布日期:2011-11-03

Clinical analysis of pulmonary fungous infection in 51 cases of mu 11 id rug- resist ant pulmonary TB( MDR-PTB)

Ye Mengh ua1,Zhang Zhongshun2, Yang Yan2, Liu Zhibin2   

  1. 1. YE Menghua . Department of pneu mology,Second ly Peopie's Hospital of Huang shi, Hu Bei 435002,China ;2. Zhang Zhongshun , Yang Yan .Liu Zhibin . DepartmerU of pneumology , Tongji University A ffiliated Shanghai Pulmonary,ShangHai,200433,China
  • Online:2009-12-10 Published:2011-11-03

摘要: 目的探讨耐多药肺结核继发肺部真菌感染的危险因素、临床特点及诊治方法,以提高对2病并存时临床表现的认识和综合处理的能力。方法回顾湖北黄石市二医院2002年以来收治的51例耐多药肺结核合并肺部真菌感染的病历资料,并进行分析。结果合并肺部真菌感染的耐多药肺结核均有明显易感因素,其临床特点:结核病史长;复治病例多;年龄偏大;肺部病变广泛,空洞多,病情较重;主要致病真菌为念珠菌。结论耐多药肺结核易继发肺部真菌感染,提高对2病并存的认识,有利于耐多药肺结核病的控制及降低死亡率。

关键词: 结核,肺/并发症, 结核,抗多种药物性/并发症, 肺疾病,真菌性

Abstract: Objective To study the risk factors,clinical characteristics and Methods of diagnosis and treatment of secondary fungal infection in MDR-PTB cases in order to improve the recognition and treatment of the coexistence of two diseases. Methods Fifty-one cases of MDR-PTB compli-cated with fungi infection in our department from 2002 were retrospectively analyzed. Results Fifty-one cases had susceptible factors of fungus infection. The major clinical features were as follows: they had a long history of tuberculosis; usually occurred in older patients;they had extensive range of lesions and many cavities in lungs; Their diagnosis depended on the examination of pathogenic organisms, type of fungi in 51 cases was Candida Albicans. Conclusion It is common that fungal infection occurred in MDR-PTB cases. Improving the recognition on the two diseases will be contribute to MDR-PTB control and reduce death rate.

Key words: tuberculosis, pulmonary/complication, tuberculosis,multidrug-resistant/complication, lung disease, fungus